Neuronal Activity of the Human Basal Ganglia in Parkinsonism Compared to Other Motor Disorders
To elucidate the function of the basal ganglia in human disease states, we have recorded their spontaneous neuronal activity during the course of stereotactic thalamotomy and more recently pallidotomy for Parkinson’s disease and other kinds of involuntary movement. The activity of the basal ganglia was correlated with that of the lateral oral thalamus to which the internal segment of the globus pallidus conveying information from the striatum is known to project. The results will be interpreted taking into account recent knowledge about this pallido-striato-thalamic connection.
KeywordsBasal Ganglion Caudate Nucleus Spontaneous Activity Essential Tremor Globus Pallidus
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