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Activity of Monkey Striatal and Dopamine Neurons During the Performance of Delayed Response Tasks

  • Wolfram Schultz
  • Paul Apicella
  • Tomas Ljungberg
  • Ranulfo Romo
Part of the Advances in Behavioral Biology book series (ABBI, volume 41)

Abstract

The striatum (caudate nucleus and putamen) lies at the crossroads of major forebrain centers involved in the organization of behavioral output. It receives afferents from limbic structures and from association and motor cortical areas dealing with the cognitive and motivational control of behavior, the preparation of behavioral acts and the control of ongoing movements. Since a major part of basal ganglia output is directed back to the frontal lobe, the functions of the striatum are intimately linked to those of prefrontal, premotor and motor cortex. The striatum is also innervated by midbrain dopamine neurons which are involved in basic behavioral activating processes and goal-directed behavior. The study of behavioral deficits in Parkinsonian patients and experimentally lesioned animals demonstrates that the intact striatal dopamine innervation is important for the expression of striatal behavioral control functions.

Keywords

Dopamine Neuron Ventral Striatum Sustained Activity Striatal Neuron Behavioral Reaction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1994

Authors and Affiliations

  • Wolfram Schultz
    • 1
  • Paul Apicella
    • 1
  • Tomas Ljungberg
    • 1
  • Ranulfo Romo
    • 1
  1. 1.Institut de PhysiologieUniversité de FribourgFribourgSwitzerland

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