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Cytosolic Calcium Transport During Myocardial Protection

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Purines and Myocardial Protection

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 181))

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Abstract

Myocardial ischemia occurs as the result of attenuation or cessation of coronary blood flow such that oxygen delivery to the myocardium is insufficient to meet oxygen requirements (1,2). In global myocardial ischemia coronary blood flow is completely obstructed resulting in the termination of substrate delivery and the discontinuation of catabolite removal. While it is generally accepted that the cessation of coronary blood flow and thus, oxygen delivery is the initial step in the process leading to myocardial ischemic injury, the sequential progression of events following the initial insult remain controversial.

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Author information

Authors and Affiliations

  1. Division of Cardiothoracic Surgery, New England Deaconess Hospital, and Harvard Medical School, Boston, Massachusetts, USA

    James D. McCully, Takuro Tsukube, Irvin B. Krukenkamp & Sidney Levitsky

Authors
  1. James D. McCully
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  2. Takuro Tsukube
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  3. Irvin B. Krukenkamp
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  4. Sidney Levitsky
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Editor information

Editors and Affiliations

  1. Cardiothoracic Division, Department of Surgery, Box 890532, MCV Station, Richmond, VA, 23298-0532, USA

    Anwar-Saad A. Abd-Elfattah MS, Ph.D.

  2. Department of Surgery, Medical College of Virginia, Richmond, Virginia, 23298-0532, USA

    Andrew S. Wechsler M.D.

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© 1996 Kluwer Academic Publishers

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McCully, J.D., Tsukube, T., Krukenkamp, I.B., Levitsky, S. (1996). Cytosolic Calcium Transport During Myocardial Protection. In: Abd-Elfattah, AS.A., Wechsler, A.S. (eds) Purines and Myocardial Protection. Developments in Cardiovascular Medicine, vol 181. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0455-5_35

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  • DOI: https://doi.org/10.1007/978-1-4613-0455-5_35

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8056-6

  • Online ISBN: 978-1-4613-0455-5

  • eBook Packages: Springer Book Archive

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