Cell Surface Molecules of Pathogenic and Nonpathogenic Entamoeba Histolytica and their Relation to Virulence
In recent years it has become increasingly clear that human infections with Entamoeba histolytica are caused by two types of morphologically indistinguishable trophozoites (McKerrow, 1992; Mirelman, 1992). Symptomatic disease is always associated with the pathogenic type (P), whereas the nonpathogenic (NP) ameba or Entamoeba dispar as many prefer to name it, usually behaves more as a commensal that does not cause symptoms. The correlation, however, between the clinical picture of the patient and the identity of the type of parasite with which he is infected, does not always fit. This complication may be due to the fact that both P and NP types of amebae can sometimes be present in the same stool, as has been recently reported for quite a number of cases (Acuna-Soto, et al. 1993; Walderich et al. 1995).
KeywordsEntamoeba Histolytica Autonomous Replication Sequence Pathogenic Type Histolytica Strain Entamoeba Dispar
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