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Toward Anti-Adhesion Therapy for Microbial Diseases pp 9–24Cite as

Anti-Adhesion and Diagnostic Strategies for Oro-Intestinal Bacterial Pathogens

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Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 408))

Abstract

Bacteria, viruses and eukaryotic cells bind to carbohydrate and protein receptors via cell adhesion molecules (Sharon and Lis, 1993). Adhesion is an essential step in microbial colonization and the development of infections, as well as in cell to cell communication, which affects leukocyte migration and tissue development (Paulson, 1993; Lasky, 1993). Anti-adhesion agents, such as carbohydrate and peptide receptor mimetics, thus represent potential therapeutic agents for the treatment of microbial infections, cancer and inflammatory diseases.

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Authors and Affiliations

  1. Department of Oral Biology Faculty of Odontology, Umeå University, S-901 87, Umeå, Sweden

    Nicklas Strömberg, Thomas Borén, Per Bratt, Kristina Hallberg, Karl-Johan Hammarström, Charlotta Holm, Ingegerd Johansson, Magdalena Järvholm, Tong Li, Mats Ryberg & Golnar Zand

  2. Department of Organic Chemistry 2 Lund Institute of Technology, University of Lund, P.O. Box 124, S-221 00, Lund, Sweden

    Stefan Ahlfors & Jan Kihlberg

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  1. Nicklas Strömberg
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  2. Stefan Ahlfors
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  3. Thomas Borén
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  4. Per Bratt
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  5. Kristina Hallberg
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  6. Karl-Johan Hammarström
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  9. Magdalena Järvholm
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  11. Tong Li
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Editors and Affiliations

  1. The Hebrew University — Hadassah Medical School, Jerusalem, Israel

    Itzhak Kahane

  2. Tel Aviv University — Sackler Medical School, Tel Aviv, Israel

    Itzhak Ofek

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© 1996 Plenum Press, New York

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Strömberg, N. et al. (1996). Anti-Adhesion and Diagnostic Strategies for Oro-Intestinal Bacterial Pathogens. In: Kahane, I., Ofek, I. (eds) Toward Anti-Adhesion Therapy for Microbial Diseases. Advances in Experimental Medicine and Biology, vol 408. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0415-9_2

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  • DOI: https://doi.org/10.1007/978-1-4613-0415-9_2

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