Abstract
In 1953 a bitter-tasting compound was isolated from oats (Mohr, 1953). The compound had saponin features such as hemolytic activity and foaming ability. Rohrlich and Train (1954) determined the sugar components to be rhamnose and glucose and found that the aglycon had a steroid structure. Tschesche and Schmidt (1966) proposed a name for the saponins in oats — avenacosides. Later the structure was elucidated for two oat saponins, avenacoside A and B (Tschesche et al., 1969; Tschesche and Lauven, 1971), both of which are bisdesmosidic (Fig. 1). The sugar residues containing glucose and rhamnose are linked to a steroid aglycon, nuatigenin. Avenacoside B contains one more glucose unit than avenacoside A.
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References
Alvarez, J.R. and Torres-Pinedo, R., 1982, Interactions of soybean lectin, soya saponins and glycinin with rabbit jejunal mucosa in vitro, Pediatr. Res. 16:728.
Atkinson, H.A.C., Grigoriadou, F. and Miller, K., 1994, Enhancement of oral sensitisation to food allergens by the bioactive plant constituent Gypsophila saponin in the brown Norway rat, in: Biochemical Biomarkers in Environmental Toxicology, abstract booklet, University of Cambridge, Cambridge, U.K.
Beynen, A.C., 1990, The mongolian gerbil in cholesterol metabolism research, in: Symposium ilber Hamster und Gerbil, Detmold.
Curl, C.L., Price, K.R. and Fenwick, G.R., 1985, The quantitative estimation of saponin in pea (Pisum sativum L.) and soya (Glycine max), Food Chem. 18:241.
Davidson, M.H., Dugan, L.D., Burns, J.H., Bova, J., Story, K. and Drennan, K.B., 1991, The hypocholesterolemic effects of β-glucan in oatmeal and oat bran, J. Am. Med. Assn. 265:1833.
Fässler, L., Lichtenthaler, H.K., Gruiz, K. and Biacs, P., 1984, Accumulation of saponins and sterols in Avena seedlings under high—light and low—light growth conditions, Developm. Plant Biol 9:225.
Fenwick, D.E. and Oakenfull, D., 1983, Saponin content of food plants and some prepared foods, J. Sci. Food Agric. 34:186.
Frølich, W. and Nyman, M., 1988, Minerals, phytate and dietaiy fibre in different fraction of oat—grain, J. Cereal Sci. 7:73.
Gee, J.M. and Johnson, I.T., 1988, Interactions between hemolytic saponins, bile salts and small intestinal mucosa in the rat, J. Nutr. 118:1391.
Gee, J.M., Price, K.R., Ridout, C.L., Wortley, G.M., Hurrell, R.F. and Johnson, I.T., 1993, Saponins of quinoa (Chenopodium quinoa): effects of processing on their abundance in quinoa products and their biological effects on intestinal mucosal tissue, J. Food Sci. Agric. 63:201.
Grünweller, S. and Kesselmeier, J., 1985, Characterization of a membrane—bound β-glucosidase responsible for the activation of oat leaf saponins, Phytochemistry 24:1941.
Harwood, H.J., Chandler, C.E., Pellarin, L.D., Bangerter, F.W., Wilkins, R.W., Long, C.A., Cosgrove, P.G., Malinow, M.R., Marzetta, C.A., Pettini, J.L., Savoy, Y.E. and Mayne, J.T., 1993, Pharmacologic consequences of cholesterol absorption inhibition: alteration in cholesterol metabolism and reduction in plasma cholesterol concentration induced by the synthetic saponin β-tigogenin cellobioside (CD-88818; tiqueside), J. Lipid Res. 34:377.
Ireland, P.A., Dziedzic, S.Z. and Kearsley, M.W., 1986, Saponin content of soya and some commercial soya products by means of high—performance liquid chromatography of the sapogenins, J. Sci. Food Agric. 37:694.
Jenkins, K.J. and Atwal, A.S., 1994, Effects of dietary saponins on fecal bile acids and neutral sterols, and availability of vitamins A and E in the chick, J. Nutr. Biochem. 5:134.
Johnson, I.T., Gee, J.M., Price, K., Curl, C. and Fenwick, G.R., 1986, Influence of saponins on gut permeability and active nutrient transport in vitro, J. Nutr. 116:2270.
Jood, S., Chauhan, B.M. and Kapoor, A.C., 1986, Saponin content of chickpea and black gram: varietal differences and effects of processing and cooking methods, J. Sci. Food Agric. 37:1121.
Kataria, A., Chauhan, B.M. and Gandhi, S., 1988, Effect of domestic processing and cooking on the antinutrients of black gram, Food Chem. 30:149.
Kesselmeier, J. and Strack, D., 1981, High performance liquid chromatographic analysis of steroidal saponins from Avena sativa L, Z. Naturforsch. 36c: 1072.
Livingston, A.L., Knuckles, B.E., Teuber, L.R., Hesterman, O.B. and Tsai, L.S., 1984, Minimizing the saponin content of alfalfa sprouts and leaf protein concentrates, in: Nutritional and Toxicological Aspects of Food Safety, Plenum Press, New York.
Mohr, W., 1953, Über die Qualitätsbeeinflussung von Haferzeugnissen (III), Dtsch. Lebensmittel— Rundsch. 49:127.
Ng, K. R., Price, K.R. and Fenwick, G.R., 1994, A TLC method for the analysis of quinoa (Chenopodium quinoa) saponins, Food Chem. 49:311.
Nicolosi, R.J., Marlett, J.A., Morello, A.M., Flanagan, S.A. and Hegsted, D.M., 1981, Influence of dietary unsaturated and saturated fat on the plasma lipoproteins of mongolian gerbils, Atherosclerosis 38:359.
Oakenfull, D.G., Fenwick, D.E., Hood, R.L., Topping, D.L., Illman, R.L. and Storer, G.B., 1979, Effects of saponins on bile acids and plasma lipids in the rat, Br. J. Nutr. 42:209.
Oakenfull, D., Topping, D.L., Illman, R.J. and Fenwick, D.E., 1984, Prevention of dietary hypercholesterolaemia in the rat by soya bean and quillaja saponins, Nutr. Rep. Int. 29:1039.
Oakenfull, D. and Sidhu, G.S., 1990, Could saponins be a useful treatment for hypercholesterolaemia?, Eur. J. Clin. Nutr. 44:79.
Önning, G., Asp, N-G. and Sivik, B., 1993, Saponin content in different oat varieties and in different fractions of oat grain, Food Chem. 48:251.
Önning, G., Juillerat, M.A., Fay, L. and Asp, N-G., 1994, Degradation of oat saponins during processing — effect of pH, stainless steel and iron at different temperatures, J. Agric. Food Chem. 42:2578.
Önning, G. and Asp, N-G., 1995, Effect of oat saponins on plasma and liver lipids in gerbils and rats, Br. J. Nutr. 73:275.
Pantzar, N., Westrom, B.R., Luts, A. and Lundin, S., 1993, Regional small—intestinal permeability in vitro to different—sized dextrans and proteins in the rat, Scand. J. Gastroenterol. 28:205.
Potter, J.D., Illman, R.J., Calvert, G.D., Oakenfull, D.G. and Topping, D.L., 1980, Soya saponins, plasma lipids, lipoproteins and fecal bile acids: a double blind cross—over study, Nutr. Rep. Int. 22:521.
Potter, S.M., Jimenez-Flores, R., Pollack, J., Lone, T.A. and Berber-Jimenez, M.D., 1993, Protein—saponin interaction and its influence on blood lipids, J. Agric. Food Chem. 41:1287.
Price, K.R., Curl, C.L. and Fenwick, G.R., 1986, The saponin content and sapogenol composition of the seed of 13 varieties of legume, J. Sci. Food Agric. 37:1185.
Price, K.R., Johnson, I.T. and Fenwick, G.R., 1987, The chemistry and biological significance of saponins in foods and feedingstuffs, CRC Crit. Rev. Food Sci. Nutr. 26:27.
Ripsin, C.M., Keenan, J.M., Jacobs, D.R., Elmer, P.J., Welch, R.R., Van Horn, L., Liu, K., Turnbull, W.H., Thye, F.W., Kestin, M., Hegsted, M., Davidson, D.M., Davidson, M.H., Dugan, L.D., Demark-Wahnefried, W. and Beling, S., 1992, Oat products and lipid lowering, a meta-analysis, J. Am. Med. Assn. 267:3317.
Rohrlich, M. and Train, G., 1954, Isolierung eines bitterschmeckenden Glycosids aus Hafer, Z. Lebensmittel — Unters. u. Forschung 345.
Rotenberg, S. and Eggum, B.O., 1986, The effect of purified pectins with and without saponins in the diet on selected lipid parameters in liver and blood plasma of rats, Acta Agric. Scand. 36:211.
Ruales, J. and Nair, B.M., 1993, Saponins, phytic acid, tannins and protease inhibitors in quinoa (Chenopodium quinoa, Willd) seeds, Food Chem. 48:137.
Sharma, A. and Sehgal, S., 1992, Effect of processing and cooking on the antinutritional factors of faba bean (Viciafaba), Food Chem. 43:383.
Shinnick, F.L., Ink, S.L. and Marlett, J.A., 1990, Dose response to a dietary oat bran fraction in cholesterol—fed rats, J. Nutr. 120:561.
Sidhu, G.S., Upson, B. and Malinow, M.R., 1987, Effects of soy saponins and tigogenin cellobioside on intestinal uptake of cholesterol, cholate and glucose, Nutr. Rep. Int. 35:615.
Southon, S., Johnson, I.T., Gee, J.M. and Price, K.R., 1988, The effect of Gypsophila saponins in the diet on mineral status and plasma cholesterol concentration in the rat, Br. J. Nutr. 59:49.
Stark, A. and Madar, Z., 1993, The effect of an ethanol extract derived from fenugreek (Trigonella foenum—graecum) on bile acid absorption and cholesterol levels in rats, Br. J. Nutr. 69:277.
Temmerman, A.M., Vonk, R.J., Niezen-Koning, K., Berger, R. and Fernandes, J., 1988, Long—term and short—term effects of dietary cholesterol and fats in the mongolian gerbil, Ann. Nutr. Metab. 32:177.
Topping, D.L., Trimble, R.P., Illman, R.J., Potter, J.D. and Oakenfull, D.G., 1980, Prevention of dietary hypercholesterolemia in the rat by soy flour high and low in saponins, Nutr. Rep. Int. 22:513.
Tschesche, R. and Schmidt, W., 1966, Zwei neue Saponine der oberirdischen Teile des Hafers (Avena sativa) mit Nuatigenin als Aglykon, Z. Naturforsch. 21b: 896.
Tschesche, R., Tauscher, M., Fehlhaber, H-W. and Wulff, G., 1969, Avenacosid A, ein bisdesmosidisches Steroid—saponin aus Avena sativa, Chem. Ber. 102:2072.
Tschesche, R. and Lauven, P., 1971, Avenacosid B, ein zweites bisdesmosidisches Steroid—saponin aus Avena sativa, Chem. Ber. 104:3549.
Tschesche, R. and Wiemann, W., 1977, Desgluco—avenacosid-A und -B, biologisch aktive Nuatigeninglycoside, Chem. Ber. 110:2416.
Wang, Q., Pantzar, N., Jeppsson, B., Weström, B.R. and Karlsson, B.W., 1994, Increased intestinal marker absorption due to regional permeability changes and decreased intestinal transit during sepsis in the rat. Scand. J. Gastroenterol. 28:1001.
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Önning, G., Asp, NG. (1996). Analysis, Heat Stability and Physiological Effects of Saponins from Oats. In: Waller, G.R., Yamasaki, K. (eds) Saponins Used in Food and Agriculture. Advances in Experimental Medicine and Biology, vol 405. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0413-5_31
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DOI: https://doi.org/10.1007/978-1-4613-0413-5_31
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