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Proton and Carbon-13 NMR Studies of Steroids and Triterpenes

  • Geoffrey A. Cordell
  • Long-Ze Lin
  • Roberto R. Gil
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 405)

Abstract

Steroids and triterpenes are common constituents of higher and lower plants, as well as marine flora and fauna. Derived from mevalonic acid with squalene as an intermediate, their skeletal diversity is essentially unmatched. Some of these compounds are important as mammalian hormones (testosterone, estrone), while others are potent toxic agents either as molluscicides, insecticides or as cytotoxic agents. Thus, as well as chemical diversity, these compounds also represent biological diversity in their mode of action. Some of the compounds, for example beta-sitosterol, are probably almost ubiquitous in the plant kingdom, indicating that while there may be many selective biosynthetic pathways depending on a particular taxonomic and ecologic niche, there is also a pathway which may be primordial in nature remaining unchanged and common to all plants.

Keywords

Oleanolic Acid Nuclear Magnetic Resonance Spectroscopy Triterpenoid Saponin Nuclear Magnetic Resonance Technique Methyl Resonance 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • Geoffrey A. Cordell
    • 1
  • Long-Ze Lin
    • 1
  • Roberto R. Gil
    • 1
  1. 1.Program for Collaborative Research in the Pharmaceutical Sciences Department of Medicinal Chemistry and Pharmacognosy College of PharmacyUniversity of Illinois at ChicagoChicagoUSA

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