Chemistry and Biological Activity of Triterpenoid Glycosides from Medicago Sativa
Alfalfa [Medicago sativa L.,(Leguminosae)] is of interest as a fodder plant and grown on large areas in many world regions. In Uzbekistan alfalfa is widely cultivated in crop rotation with cotton and this makes the plant an important raw material. Alfalfa saponin is well known to influence animal organisms1,2, and to affect insect and fungus growth3. It was shown by Slotwinska4 that the saponins induced the reduction of mitotic index, viability, and growth of cells in L-cells culture. Study of the growth-retarding activity of alfalfa saponins on higher plants was by Waller, Jurzysta and Thorne5. Owing to this we have studied triterpene glycosides of this plant of great national economic significance. Objects of study were alfalfa roots and leaves. As a result of thin layer chromatography (TLC) there have been discovered 13 glycosides in the roots and 10 in the leaves. Qualitative compositions of glycosides from plant organs are different, and do not have identical components. The structures were established for 10 root glycosides6.
KeywordsMedicagenic Acid Triterpene Glycoside Wheat Coleoptile Alfalfa Root Crude Saponin
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