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A Method for the in Vivo Quantitation of Angiogenesis in the Rabbit Corneal Model

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Molecular, Cellular, and Clinical Aspects of Angiogenesis

Part of the book series: NATO ASI Series ((NSSA,volume 285))

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Abstract

Angiogenesis is stimulated by a variety of factors and underlies the pathology of many disease states, including cancer and blinding eye disease. It is often necessary to quantitate the angiogenic response to various stimuli and determine the efficacy of putative inhibitory agents. We describe a non-invasive method for measuring angiogenesis in a rabbit corneal model with precision and ease, regardless of geometrical irregularities in the vessel growth pattern.

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Authors and Affiliations

  1. Department of Cell Biology, The Scripps Research Institute, La Jolla, CA, 92037, USA

    Robert W. Shaffer & Martin Friedlander

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  1. Robert W. Shaffer
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  2. Martin Friedlander
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Editors and Affiliations

  1. University of Patras Medical School, Patras, Greece

    Michael E. Maragoudakis

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© 1996 Plenum Press, New York

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Shaffer, R.W., Friedlander, M. (1996). A Method for the in Vivo Quantitation of Angiogenesis in the Rabbit Corneal Model. In: Maragoudakis, M.E. (eds) Molecular, Cellular, and Clinical Aspects of Angiogenesis. NATO ASI Series, vol 285. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0389-3_22

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  • DOI: https://doi.org/10.1007/978-1-4613-0389-3_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8030-6

  • Online ISBN: 978-1-4613-0389-3

  • eBook Packages: Springer Book Archive

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