Effects of DMSP and Related Compounds on Behavior, Growth and Stress Resistance of Fish, Amphibians and Crustaceans

  • Kenji Nakajima


Recording methods for determining the striking behavior of fish were developed. Among a number of sulfonium compounds tested, dimethylsulfoniopropionate (DMSP) proved to elicit the strongest effect on striking behavior of goldfish. Electrophysiological experiments revealed that DMSP stimulated the olfactory sense of carp more strongly than did glutamine. The effects of DMSP on growth and body movement of fish, amphibians, crustaceans, rats and chickens were examined. The results indicated that DMSP stimulated the growth and body movements of test organisms to varying degrees. Moreover, DMSP proved to accelerate the metamorphosis of amphibians and the molting of crustaceans. It also strengthened the resistance of fish against physical and chemical stresses and against stress-induced gastric ulcers in rats. The distribution of dimethylacetothetin (DMT)-homocysteine methyltransferase enzyme in various viscera of carp and substrate specificity of the enzyme were investigated. DMSP gave the highest specific activity as a methyl donor, as compared to other sulfonium compounds, and the highest activity of the enzyme was found in the hepotopancreas. Furthermore, dietary supplemented DMSP proved to accumulate rapidly in hepatopancreas tissues as compared to various viscera of carp. The addition of various concentrations of methionine to the diet or to the rearing water was found to promote the growth of carp and the molt of prawns but not the growth and metamorphosis of amphibians.


Rainbow Trout Glycine Betaine Dimethyl Sulfide Olfactory Response Olfactory Sense 
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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • Kenji Nakajima
    • 1
  1. 1.Laboratory of Biochemistry, Department of NutritionKoshien UniversityTakarazuka, HyogoJapan

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