Abstract
Venom is a mixture of various substances produced in a specific gland in the body of the venomous animal and introduced through a piercing injecting mechanism into the body of another animal in order to paralyze it or to kill it. In nature, venoms are employed by slow predatory animals in order to capture through an immediate paralysis their relatively fast prey organisms [1]. In the laboratory, however, venoms are employed as sources for the search of various pharmacological and mainly neurotoxic substances.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Zlotkin, E. In: Comparative Invertebrate Neurochemistry (Lunt, G.G. and Olsen R.N., Eds.) Croom Helm Publ. London pp. 256–324 (1988).
Zlotkin, E. Phytoparasitica, 19, 177 (1991).
Fainzilber, M. PhD Thesis, Hebrew Univ. (1993).
Pelhate, M. and Zlotkin, E. J. Exp. Biol., 97, 67 (1982).
Hasson, A. M.Sc. Thesis, Hebrew Univ. (1993).
Olivera, B.M., Rivier, J., Scott, J.K., Hillyard, D.R., and Cruz, L.J. J. Biol. Chem. 266, 22067 (1991).
Gray, W.R., Olivera, B.M., and Cruz, L.J. Annu. Rev. Biochem. 57, 665 (1988).
Hillyard, D.R., Olivera, B.M., Woodward, S., Corpuz, G.P., Gray, W.R., Ramilo, CA., and Cruz, L.J. Biochemistry 28, 358 (1989).
Fainzilber, M., Gordon, D., Hasson, A., Spira, M.E., and Zlotkin, E. Eur. J. Biochem. 202, 589 (1991).
Hasson, A., Fainzilber, M., Gordon, D., Zlotkin, E., and Spira, M.E. Eur. J. Neurosci. 5, 56 (1993).
Gonoi, T., Hille, B., and Catterall, W.A. J. Neurosci. 4, 2836 (1984).
Gonoi, T., Ashida, K., Feller, D., Schmidt, J., Fujiwara, M., and Catterall, W.A. Mol. Pharmacol. 29, 347 (1986).
Gonoi, T., Ohizumi, Y, Kobayashi, J., Nakamura, H., and Catterall, W.A. Mol. Pharmacol. 32, 691 (1987).
Ray, R., Morrow, C.S., and Catterall, W.A. J. Biol. Chem. 253. 7307 (1978).
Catterall, W.A. Annu. Rev. Biochem. 55, 953 (1986).
Tamkun, M.M., and Catterall, W.A. Mol. Pharmacol. 19, 78 (1981).
Catterall, W.A., and Gainer, M. Toxicon 23, 497 (1985).
Willow, M., and Catterall, W.A. Mol. Pharmacol. 22, 627 (1982).
Brown, G.B. J. Neurosci. 6, 2064 (1986).
Barhanin, J., Hugues, M., Schweitz, H., Vincent, J.P., and Lazdunski, M. J. Biol. Chem. 256, 5764 (1981).
Sato, C, and Matsumoto, G. Biochem. Biophys. Res. Commun. 186, 61 (1992a).
Sato, C, and Matsumoto, G. Biochem. Biophys. Res. Commun. 186, 1158 (1992b).
Dyer, J.R., Johnston, W.L., and Dunn, R.J. Neurobiology of Aplysia Conference Abstracts, pp. 26, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY (1993).
Catterall, W.A. Pharm. Rev. 72(4) Suppl. S15 (1992).
Thomsen, W.J., and Catterall, W.A. Proc. Natl. Acad. Sci. U.S.A. 86, 10161 (1989).
Atema, J. In: Sensory Biology of Aquatic Animals (Atema, J., Fay, R.R., Popper, A.N., and Tavogla, W.N., Eds.), Springer, New York, pp. 29–56 (1988).
Carr, W.E.S. In: Sensory Biology of Aquatic Animals (Atema, J., Fay, R.R., Popper, A.N.. and Tavogla, W.N., Eds.), Springer, New York, pp. 3–27 (1988).
Williams, J.D., Holland, K.N., Jameson, D.M., and Bruening, R.C J. Chem. Ecol. 18, 2107 (1992).
Gurin, S., and Carr, W.E.S. Science 174, 293 (1971).
Rittschof, D., and Bonaventura, J. J. Chem. Ecol. 12, 1013 (1986).
Parker, G.H. J. Exp. Zool. 36, 205 (1922).
Gonor, J.J. Veliger 7, 228 (1965).
Gonor, J.J. Veliger 8, 226 (1966).
Kohn, A.J., and Waters, V Anim. Behav. 14, 340 (1966).
Berg, C.J. Am. Zool. 12, 427 (1972).
Kohn, A.J. Ecology 4, 1041 (1966).
Kohn, A.J., and Nybakken, J.W. Mar. Biol. 29, 211 (1975).
Olivera, B.M., Rivier, J., Clark, C, Ramilo, C.A., Corpuz, G.P. Abogadie, F.C., Mena, E.E., Woodward, S.R., Hillyard, D.R., and Cruz, L. J. Science 249, 257 (1990).
Fainzilber, M., and Zlotkin, E. Toxicon 30, 465 (1992).
Fainzilber, M., Kofman, O., Zlotkin, E., and Gordon, D. J. Biol. Chem. 269, 2574 (1994).
Rittschof, D. Amer. Malac. Bull. Spec. Ed. 1, 111 (1965).
Morse, D.E. Bull. Mar. Sci. 37, 697 (1985).
Morse, D.E. Bull. Mar. Sci. 46, 465 (1990).
Painter, S.D. Biol. Bull. 183, 165 (1992).
Weiland, G.A. and Molinoff, P.B. Life Sci. 29, 313 (1981).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Plenum Press, New York
About this chapter
Cite this chapter
Zlotkin, E., Gordon, D., Napchi-Shichor, I., Fainzilber, M. (1996). Metamorphoses of a Conotoxin. In: Singh, B.R., Tu, A.T. (eds) Natural Toxins 2. Advances in Experimental Medicine and Biology, vol 391. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0361-9_33
Download citation
DOI: https://doi.org/10.1007/978-1-4613-0361-9_33
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-8016-0
Online ISBN: 978-1-4613-0361-9
eBook Packages: Springer Book Archive