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Vaccines pp 85-95 | Cite as

Feline Immunodeficiency Virus as a Vaccine Model

  • M. J. Hosie
  • O. Jarrett
Part of the Nato Science Series book series (NSSA, volume 282)

Abstract

Acquired immunodeficiency syndrome (AIDS) is a lentivirus-induced disease caused by the human immunodeficiency virus (HIV) (Barre-Sinoussi et al, 1983; Gallo et al, 1984). HIV infection occurs worldwide and is a major threat to world health. There is, therefore, an urgent requirement for the development of effective vaccines to prevent the spread of the virus. However, there are many obstacles to the production of such a vaccine. Lentiviral infection is persistent despite the development of a vigorous immune response, there is no recovery from infection. Instead, disease almost inevitably occurs following a long latent period. Given these obstacles, it has been recognised that although vaccination may not protect completely against HIV infection, the onset of the clinical signs which result from infection may be prevented or at least delayed.

Keywords

Human Immunodeficiency Virus Human Immunodeficiency Virus Infection Acquire Immune Deficiency Syndrome Simian Immunodeficiency Virus Feline Immunodeficiency Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1995

Authors and Affiliations

  • M. J. Hosie
    • 1
  • O. Jarrett
    • 1
  1. 1.Department of PathologyUniversity of Glasgow BearsdenGlasgowScotland

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