Cellular Diversity of Human Placental Vessel Wall
The basic cell type of the placental villus core is undifferentiated stromal cells. Beginning in the early periods of vascularization, these show a differentiation towards the whole variety of villus stromal cells (Benirschke and Kaufmann, 1990; Demir and Erbengi, 1984), and form the vessels (Demir et al, 1989). From these new cell varieties; fibroblasts, reticulum cells, pericytes, endothelial cells, myofibroblasts, Hofbauer cells and embyronic plasma cells and the entire stromal architecture is constructed. From the early periods of pregnancy, many developmental changes and differentiations, which continue in various directions, take place in the villus core (Benirschke and Kaufmann, 1990; Demir et al, 1989). The cellular variability of placental vessels wall is very rarely examined depending on the solution embryonal cell potence and differentiation processes.
- Benirschke, K. and Kaufmann, P., 1990, Pathology of human placenta, P.P.-15–65, Springer-Verlag, New York, Heidelberg, Berlin, London.Google Scholar
- Demir, R., and Erbengi, T., 1992, Structural features of nephropneumonic-like units in the full term human placental barrier. J. Scanning Microscopy 14: 71.Google Scholar
- Demir, et al., 1992, Distribution of myofibroblast-like cells in human placental stem villi. Electron Microscopy Vol. 3: 409–510.Google Scholar
- Kaufinann, P., 1982, Development and differentiation of the human placental villous tree. Bibl. Anat. 22: 29–39.Google Scholar
- Kohnen, G., 1994, Immunohistochemische Charakterisierung der myofibroblasten diferenzierung in der menschlichen placenta. Doctora pHD thesis, Aachen.Google Scholar