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Some Evolutionary, Morphoregulatory, and Functional Aspects of the Immune—Neuroendocrine Circuitry

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Immunopharmacology Reviews Volume 2

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Abstract

David Wilson Talmage, one of the most important pioneers of the molecular biology of immunoregulation, in discussing recently (1988) what is beyond molecular immunology, poses the following questions:

What will we study after we understand all the genes and their products that impact on the immune system? Surely, in a few years we will understand how lymphocytes differentiate and are activated, how they synthesize, secrete, kill, migrate. What will we study then? My prediction is that immunology will then have its greatest challenge. How can we put it all together for the benefit of mankind? How will we prevent allergies, autoimmunity, transplant rejection, and how will we cure cancer? The coming era of immunology will be a stage of synthesis–a return to Stage 1 and the immunology of the whole animal. [Talmage, 1988]

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  1. Departments of Internal Medicine, Neurology, Pharmacology, and Environmental and Occupational Health, University of South Florida Colleges of Medicine and Public Health, Tampa, Florida, 33612, USA

    Andor Szentivanyi & Richard F. Lockey

  2. Department of Internal Medicine, University of South Florida Colleges of Medicine and Public Health, Tampa, Florida, 33612, USA

    Christine M. Abarca

  3. Department of Environmental and Occupational Health, University of South Florida Colleges of Medicine and Public Health, Tampa, Florida, 33612, USA

    Stuart M. Brooks

  4. Department of Neurology, University of South Florida Colleges of Medicine and Public Health, Tampa, Florida, 33612, USA

    Leon D. Prockop

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Szentivanyi, A., Abarca, C.M., Brooks, S.M., Lockey, R.F., Prockop, L.D. (1996). Some Evolutionary, Morphoregulatory, and Functional Aspects of the Immune—Neuroendocrine Circuitry. In: Hadden, J.W., Szentivanyi, A. (eds) Immunopharmacology Reviews Volume 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0349-7_12

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