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Neuropathic Viruses and Autoimmunity

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Microorganisms and Autoimmune Diseases

Part of the book series: Infectious Agents and Pathogenesis ((IAPA))

Abstract

The spectrum of viral infections of the central nervous system (CNS) or peripheral nervous system (PNS) includes acute, chronic, latent, and “slow” viral infections. There are relatively few host responses possible in the nervous system in a viral infection, so the results tend to be stereotyped. Acute or subacute viral infections usually cause within the nervous system such diseases as meningitis, acute infective encephalomyelitis, and encephalitis, as well as acute postinfectious encephalitis. “Slow virus” infections are slow due to the long incubation periods, but may not be viral in origin. They continue to be discussed with viral infections as diseases caused by infectious agents unable to propagate in host cells (Table I). The severity and characteristics of the infections with various viruses that affect that CNS are thought to reflect tropism, virulence, and the host immune response. The incubation periods and length of disease are highly variable from one virus to another and will be discussed individually.

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Author information

Authors and Affiliations

  1. Department of Pathology, University of Utah, Salt Lake City, Utah, USA, 84132

    Cynthia T. Welsh

  2. Department of Neurology, University of Utah, Salt Lake City, Utah, USA, 84132

    Robert S. Fujinami

Authors
  1. Cynthia T. Welsh
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  2. Robert S. Fujinami
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Editor information

Editors and Affiliations

  1. College of Medicine, University of South Florida, Tampa, Florida, USA

    Herman Friedman

  2. School of Hygiene and Public Health, The Johns Hopkins University, Baltimore, Maryland, USA

    Noel R. Rose

  3. University of Pisa, Pisa, Italy

    Mauro Bendinelli

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© 1996 Plenum Press, New York

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Welsh, C.T., Fujinami, R.S. (1996). Neuropathic Viruses and Autoimmunity. In: Friedman, H., Rose, N.R., Bendinelli, M. (eds) Microorganisms and Autoimmune Diseases. Infectious Agents and Pathogenesis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0347-3_7

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  • DOI: https://doi.org/10.1007/978-1-4613-0347-3_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-45236-9

  • Online ISBN: 978-1-4613-0347-3

  • eBook Packages: Springer Book Archive

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