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Abstract

Strictly, desorption is the term used to describe the transfer of atoms or molecules from a surface-adsorbed state into the gas phase. The study of pure desorption processes lies in the realm of surface science and is carried out using a well-defined sample, consisting of a submonolayer of atoms or small molecules, adsorbed to a surface of known structure. Mass spectrometrists use the term ‘desorption’ in a less rigorous sense to describe a range of techniques which are used to transfer atoms or molecules from the solid state into the gas phase. These methods include field desorption, plasma desorption, secondary ion mass spectrometry, fast atom bombardment and laser desorption. The sample is typically many monolayers thick, deposited on a crude substrate, and may consist of a mixture of complex organic molecules, one component of which acts as a matrix. In these methods, the desorption event generally results in the removal of several monolayers of material.

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References

  • Bahr, U., Deppe, A., Karas, M., Hillenkamp, F., and Giessman, U., 1992, Anal. Chem. 64:2866.

    Article  CAS  Google Scholar 

  • Bahr, U., Karas, M., and Hillenkamp, F., 1994, J. Anal.Chem. 348:783.

    CAS  Google Scholar 

  • Beavis, R.C., Lindner, J., Grotemeyer, J., and Schlag, E.W.,1988, Z. Naturforsch 43a:1083.

    Google Scholar 

  • Beavis, R.C., and Chait, B.T., 1989, Rapid Commun. Mass Spectrom. 3:233.

    Article  CAS  Google Scholar 

  • Beavis, R.C., 1992, Org. Mass. Spectrom. 27:653.

    Article  CAS  Google Scholar 

  • Billeci, T.M., and Stults, J.T., 1993, Anal.Chem. 65:1709..

    Article  CAS  Google Scholar 

  • Burlinghame, A.L., Boyd, R.K., and Gaskell, S.J., 1994, Anal.Chem. 66:634R.

    Article  Google Scholar 

  • Cable, J.R., Tubergen, M.J., and Levy, D.H., 1988, J. Am. Chem. Soc. 110:7349.

    Article  CAS  Google Scholar 

  • Cable, J.R., Tubergen, M.J., and Levy, D.H., 1989, J. Am. Chem. Soc. 111:9032.

    Article  CAS  Google Scholar 

  • Cotter, R.J., 1980, Anal. Chem. 52:1767.

    Article  CAS  Google Scholar 

  • Dale, M.J., Jones, A.C., Pollard, S.J.T., Rowley, A.G., and Langridge-Smith, P.R.R., 1993, Env. Sci. Technol. 27:1693.

    Article  CAS  Google Scholar 

  • Dale, M.J., Jones, A.C., Pollard, S.J.T., and Langridge-Smith, P.R.R., 1994, Analyst 119:571.

    Article  CAS  Google Scholar 

  • Dale, M.J., Downs, O.H.J., Costello, K.F., Wright, S.J., Langridge-Smith, P.R.R., and Cape, N.J., 1995, Environ. Pollut. (in press).

    Google Scholar 

  • Danis, P.O., Karr, D.E., Mayer, F., Holle, A., and Watson, C.H., 1992, Org. Mass Spectrom. 27:843

    Article  CAS  Google Scholar 

  • De Vries, M.S., Hunziker, H.E., Wendt, H.R., and Saperstein, D.D.,1990, Anal. Chem. 62:2385.

    Google Scholar 

  • Eckerskorn, C., Strupart, K., Karas, M., Hillenkamp, F., and Lottspeich, F., 1992, Electrophoresis 13:664.

    Article  CAS  Google Scholar 

  • Engelke, F., Hahn, J.H., Henke, W., and Zare, R.N., 1987, Anal. Chem. 59:909.

    Article  CAS  Google Scholar 

  • Grotemeyer, J., Boesl, U., Walter, K., and Schlag, E.W., 1986, Org. Mass Spectrom., 21:645.

    Article  CAS  Google Scholar 

  • Grotemeyer, J., and Schlag, E.W., 1988, Org. Mass Spectrom. 23:388.

    Article  CAS  Google Scholar 

  • Grotemeyer, J., and Schlag, E.W., 1989, Acc. Chem. Res. 22:399.

    Article  CAS  Google Scholar 

  • Hahn, J.H., Zenobi, R., and Zare, R.N., 1987, J. Am. Chem. Soc. 109:2842.

    Article  CAS  Google Scholar 

  • Henke, W.E., Weyssenhoff, H.V., Selzle, H.L., and Schlag, E.W., 1983, Verh. Dtsch. Phys. Ges. 3:139.

    Google Scholar 

  • Hillenkamp, F., Karas, M., Beavis, R.C., and Chait, B.T., 1991, Anal. Chem. 63:1193A.

    Article  CAS  Google Scholar 

  • Karas, M., and Hillenkamp, F., 1988, Anal. Chem. 60:2299.

    Article  CAS  Google Scholar 

  • Karas, M., Ingendoh, A., Bahr, U., and Hillenkamp, F., 1989, Biomed. Environ. Mass Spectrom. 18:841

    Article  CAS  Google Scholar 

  • Keough, T., Takigiku, R., Lacey, M.P., and Purdon, M., 1992, Anal. Chem. 64:1594.

    Article  CAS  Google Scholar 

  • Koster, C., and Grotemeyer, J., 1992, Org. Mass Spectrom.27:463.

    Article  Google Scholar 

  • Kovalenko, L.J., Philippoz, J.M., Bucenell, J.R., Zenobi, R., and Zare, R.N., 1991, Space Science Reviews 56:191.

    Article  Google Scholar 

  • Lindner, B., and Seydel, U., 1985, Anal. Chem. 57:895.

    Article  CAS  Google Scholar 

  • Lubman, D.M., 1987, Anal. Chem. 59:31A.

    Article  CAS  Google Scholar 

  • Lubman, D.M., 1993, Two-step methods for separated volatilisation and laser-induced multiphoton ionisation of small biological molecules in supersonic jets, in: “Laser Ionisation Mass Analysis,” Akos, V., Renaat, G., and Adams, F., eds., Chemical Analysis Series, Vol. 24, John Wiley and Sons Inc., New York, pp. 321–368.

    Google Scholar 

  • Maechling, C.R., Clemett, S.J., Zare, R.N., and Buseck, P.R., 1993, in: “Proc. 41st ASMS Conf. Mass Spectrometry and Allied Topics,” Washington DC, 428.

    Google Scholar 

  • Mowat, I.A., and Donovan, R.J., 1995, Rapid Commun. Mass Spectrom. 9:82.

    Article  CAS  Google Scholar 

  • Nordhoff, E., Ingendoh, A., Cramer, R., Overberg, A., Stahl, B., Karas, M., Hillenkamp, F., and Crain, P.F., 1992, Rapid Commun. Mass Spectrom. 6:771.

    Article  CAS  Google Scholar 

  • Posthumus, M.A., Kistemaker, P.G., Meuzelaar, M.C., and Ten Noever de Brauw, M.C.,1978, Anal. Chem.,50:985.

    Article  CAS  Google Scholar 

  • Schlag, E.W., Grotemeyer, J., and Levine, R.D., 1992, Chem. Phys. Lett. 190:521.

    Article  CAS  Google Scholar 

  • Strupat, K., Karas, M., and Hillenkamp, F., 1991, Int. J. Mass Spectrom. Ion Processes 111:89

    Article  CAS  Google Scholar 

  • Sundqvist, B.U.R., 1992, Int. J. Mass Spectrom. Ion Processes 118/119:265.

    Article  Google Scholar 

  • Tanaka, K., Waki, H., Ido, Y., Akita, S., Yoshida, Y., and Yoshida, T., 1988, Rapid Commun. Mass Spectrom. 2:151.

    Article  CAS  Google Scholar 

  • Tembreull, R., and Lubman, D.M., 1986, Anal. Chem. 58:1299.

    Article  CAS  Google Scholar 

  • van Bremen, R.B., Snow, M., and Cotter, R.J., 1983, Int. J. Mass Spectrom. Ion Phys. 49:35.

    Article  Google Scholar 

  • van Veelen, P.A., Tjaden, U.R., van der Greef, J., Ingendoh, A., and Hillenkamp, F., 1993, Chromatogr. 647:367.

    Article  Google Scholar 

  • Vertes, A., and Gijbels, R., 1993, Laser-induced thermal desorption and matrix-assisted methods, in: “Laser Ionisation Mass Analysis,” Akos, V., Renaat, G., and Adams, F., eds., Chemical Analysis Series, Vol. 24, John Wiley and Sons Inc., New York, pp. 127–175.

    Google Scholar 

  • Weyssenhoff, H.V., Selzle, H.L., and Schlag, E.W., 1985, Z. Naturschforsch., 40a:674.

    Google Scholar 

  • Wu, K.J., Steding, A., and Becker, C.H., 1993, Rapid Commun. Mass Spectrom. 7:142.

    Article  CAS  Google Scholar 

  • Zare, R.N., and Levine, R.D., 1987, Chem. Phys. Lett. 136:593.

    Article  CAS  Google Scholar 

  • Zenobi, R., 1994, Chimia 48:64.

    CAS  Google Scholar 

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© 1995 Plenum Press, New York

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Jones, A.C. (1995). Laser Desorption. In: Andrews, D.L., Demidov, A.A. (eds) An Introduction to Laser Spectroscopy. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0337-4_11

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  • DOI: https://doi.org/10.1007/978-1-4613-0337-4_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8004-7

  • Online ISBN: 978-1-4613-0337-4

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