Abstract
Adult respiratory distress syndrome (ARDS) is characterised by decreased lung compliance and functional residual capacity (FRC) and increased intrapulmonary shunting resulting in hypoxemia. The immediate treatment of this critical situation is respiratory therapy of one form or the other and various modes have been recommended since the description of the disease. Positive end expiratory pressure (PEEP) with large tidal volume (VT), which recruits atelectatic areas and increases FRC, was once suggested as the treatment of ARDS.1-6 However, this mode of ventilation may cause barotrauma and/or morphological changes due to high peak inspiratory pressures (PIP).
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References
Kumar A., Falke K.J., Geffin B., et al., 1970, Continuous positive-pressure ventilation in acute respiratory failure: effects on hemodynamics and lung function,N. Engl. J.Med. 283:1430–1436.
Falke K.J., Pontoppidan H., Kumar A., et al., 1972, Ventilation with end expiratory pressure in acute lung disease,J. Clin. Invest. 51:2315–2323.
Hedley-Whyte J., Pontoppidan H., and Morris M.J., 1966, The response of patients with respiratory failure and cardiopulmonary disease to different levels of constant volume ventilation,J. Clin. Invest. 45:1543–1554.
Ashbaugh D.G., Bigelow D.B., Petty T.L., et al., 1967, Acute respiratory distress in adults, Lancet2:319–323.
Mclntyre R.W., Lwas A.K., and Ramachandran P.R., 1969, Positive expiratory pressure plateau; improved gas exchange during mechanical ventilation,Can. Anaesth. Soc. J.16:477–486.
Levine M., Gilbert R., and Auchincloss J.H. Jr., 1972, A comparison of the effects of sighs, large tidal volumes, and positive end expiratory pressure in assisted ventilation,Scand. J. Respir. Dis. 53:101–108.
Lachmann B., Danzmann E., Haendly B., and Jonson B., 1982, Ventilator settings and gas exchange in respiratory distress syndrome. In: Prakash, O, (ed): Applied physiology in clinical respiratory care, Martinus Nijhoff Publishers, The Hague, Boston, London.
Gattinoni L., Agostoni A., Pesenti A., Pelizzola A., Rossi GR, Langer M., Vesconi S., Uziel L., Fox U., Longoni F., Kolobow T, and Damia G, 1980, Treatment of acute respiratory failure with low-frequency- positive-pressure ventilation and extracorporeal removal of C02,Lancet2:292.
Bone R.C., 1976, Compliance and dynamic characteristics curves in acute respiratory failure,Crit. Care Med. 4:173–179.
Wilson R.S., 1976, Monitoring the lung: mechanics and volume,Anaesthesiology45:135–145.
Suter P.M., Fairley H.B., and Isenberg M.D., 1978, Effect of tidal volume and positive end expiratory pressure on compliance during mechanical ventilation,Chest73:158–162.
Bone R.C., 1983, Monitoring ventilatory mechanics in acute respiratory failure,Respir. Care28:597–604.
Gattinoni L., Pesenti A., Caspani M.L., Pelizzola A., Mascheroni D., Marcolin R., Iapichino G., Langer M., Agostoni A., Kolobow T, Melrose D.G., and Damia G., 1984, The role of total static lung compliance in the management of severe ARDS unresponsive to conventional treatment,Intensive Care Med. 10:121–126.
Suter P.M., Fairley H.B., and Isenberg M.D., 1975, Optimum end-expiratory airway pressure in patients with acute pulmonary failure,N.Engl.J.Med. 292:284–289.
Gattinoni L., Pesenti A., Avalli L., Rossi F., and Bombino M., 1987, Pressure-volume curve of total respiratory system in acute respiratory failure: computed tomographic scan study,Am. Rev. Respir. Dis. 136:730–736.
Lachmann B., Robertson B., and Vogel J., 1980, In-vivo lung lavage as an experimental model of the respiratory distress syndrome,Acta Anaesthesiol. Scan. 24:231–236.
Lachmann B., Jonson B., Lindroth M., and Robertson B., 1982, Modes of artificial ventilation in severe respiratory distress syndrome: Lung function and morphology in rabbits after wash-out of alveolar surfactant.Crit. Care Med. 10:724–732.
Gattinoni L., Pesenti A., Mascheroni D., Marcolin R., Fumagalli R., Rossi F., Iapichino G., Romagnoli G., Uziel L., Agostoni A., Kolobow T, and Damia G., 1986, Low-frequency positive-pressure ventilation with extracorporeal C02removal in severe acute respiratory failure,JAMA256:881–886.
Gattinoni L., Kolobow T, Tomlinson T, Iapichino G, Samaja M., White D., and Pierce J., 1978, Low-frequency positive pressure ventilation with extracorporeal carbon dioxide removal (LFPPV-ECC02R): an experimental study,Anesth. Analg. 57:470–477.
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© 1996 Plenum Press,New York
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Kesecioğlu, J. et al. (1996). Effects of Volume Controlled Ventilation with Peep, Pressure Regulated Volume Controlled Ventilation and Low Frequency Positive Pressure Ventilation with Extracorporeal Carbon Dioxide Removal on Total Static Lung Compliance and Oxygenation in Pigs with ARDS. In: Ince, C., Kesecioglu, J., Telci, L., Akpir, K. (eds) Oxygen Transport to Tissue XVII. Advances in Experimental Medicine and Biology, vol 388. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0333-6_81
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DOI: https://doi.org/10.1007/978-1-4613-0333-6_81
Publisher Name: Springer, Boston, MA
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