O2 Flux Optode

A New Sensing Principle to Determine the Oxygen Flux and Other Gas Diffusions
  • D. W. Lübbers
  • T. Köster
  • G. A. Holst
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 388)


By applying a transparent test membrane of defined diffusion properties between two layers of optical chemical oxygen sensors, O2 optodes, the measurement of oxygen diffusion, the oxygen flux, across the membrane becomes possible.1 The optode has the inherent advantage towards the established method of electrochemical oxygen measurements that the sensor is permeable for oxygen and does not consume the analyte. With this new sensing principle (Fig. 1) the O2 flux is calculated as the product of the oxygen partial pressure (pO2) difference between both sides of the membrane and the diffusion properties of the membrane. This sensor can be used to measure the 02 flux in different applications, e. g. the O2 flux into human tissue, into technical compartments as bioreactors or into biological systems. The selectivity of the proposed sensor is strongly influenced by the choice of an appropriate test membrane. With suitable indicators it is also possible to measure other gas fluxes. So, this principle opens up a new field of flux measurements.


Fluorescence Lifetime Flux Measurement Oxygen Flux Sensor Head Sensor Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • D. W. Lübbers
    • 1
  • T. Köster
    • 1
  • G. A. Holst
    • 1
  1. 1.Max-Planck-Institut für Molekulare PhysiologieDortmundGermany

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