Abstract
Today, repair of congenital heart defects has become a routine operation with low mortality and morbidity in many subgroups of anomalies1. The knowledge that the ventricular myocardium continues to develop and conditions itself according to the loads present and that this mechanism can influence the long-term outcome in many cardiac anomalies, stress the operations towards infantile and neonatal age groups2,3. This, in turn, stresses the importance of the possible damage to the other organs and systems still developing at the time of cardiopulmonary bypass (CPB). While myocardial protection attempted by lowering the energy demands through topical cold and chemical cardioplegia1,4,5, the protection of other systems, including central nervous system (CNS), remains dependent on the oxygenation and the local wash out of metabolites by means of CPB.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cardiac Surgery Ed.by Kirklin-JW and Barrat-Boyes-BG Second Ed. Churchill Livingstone 1993.
Simple transposition of great arteries: The arterial switch operation in neonates. Castenada-AR in Pediatric Cardiac Operations Ed. by Jacobs-ML and Norwood-WI. Butterworth-Heinemann 1992 p. 1–12.
Physiologic repair of aortic atresia-hypoplastic left heart syndrome. Norwood-WI; Lang-P; Hansen-D N-Engl-J-Med. 1983; 308: 23.
The effect of hypothermic ischemia on recovery of left ventricular function and preload reserve in the neonatal heart. Bove-EL; Gallagher-KP; Drake-DH et al. J-Thorac-Cardiovasc-Surg. 1988; 95:814.
The additive protective effects of hypothermia and chemical cardioplegia during ischemic cardiac arrest in the rat. Hearse-DJ; Stewart-DA; Braimbridge-MV J-Thorac-Cardiovase-Surg. 1980; 79:39.
Oxygen consumption during cardiopulmonary bypass with moderate hypothermia in man. Harris-EA; Seeyle-ER; Squire-AW Brit-J-Anaesth. 1971; 43:1113–20.
On the availability of oxygen to the body during cardiopulmonary bypass in man. Harris-EA; Seeyle-Er;Barrat-Boyes-BG Brit-J-Anaesth 1974; 46:425–31.
Normothermia versus hypothermia for whole body perfusion: Effects on myocardial and body metabolism. Moffit-EA; Sessler-AD; Molnar-GD; McGoon-DC Anaesthesia and Analgesia 1971; 50 (4) Jul—Aug:505–16.
The effects of profound hypothermia on preservation of cerebral ATP content during circulatory arrest. Kramer-R; Sanders-A; Lesage-A; Woodhall-B; Sealy-W J-Thorac-Cardiovasc-Surg. 1968; 56:699.
Oxygen consumption of animals and tissues as a function of temperatures. Fuhrman-GJ;Fuhrman-FA J-Gen-Physiol. 1959; 42:715.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Plenum Press New York
About this chapter
Cite this chapter
Tekinalp, H., Barlas, S., Tireli, E., Çavuşodlu, H., Barlas, C. (1996). Oxygen Supply during Cardiopulmonary Bypass (CPB) in Cyanotic Patients. In: Ince, C., Kesecioglu, J., Telci, L., Akpir, K. (eds) Oxygen Transport to Tissue XVII. Advances in Experimental Medicine and Biology, vol 388. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0333-6_64
Download citation
DOI: https://doi.org/10.1007/978-1-4613-0333-6_64
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-8002-3
Online ISBN: 978-1-4613-0333-6
eBook Packages: Springer Book Archive