In Vivo Measurement of Oxygen Pressure Using 19F-NMR Imaging
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 388)
Nuclear magnetic resonance (NMR) of the fluorine nucleus is an in vivo method to measure non-invasively oxygen pressures. The measurement is based on the effect that the longitudinal relaxation rate (R1 = 1/T1) increases linearly with the partial oxygen pressure (pO2) when the temperature is kept constant [1,2]:
The calibration constants A and B depend strongly on temperature, magnetic field strength, the fluorinated subtances, the resonance line used for imaging, and on the tissue type
$$R_1 = 1/T_1 = A + B \times pO_2 $$
KeywordsNuclear Magnetic Resonance Partial Oxygen Pressure Oxygen Carrier Calibration Constant Chemical Shift Artifact
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Plenum Press, New York 1996