Oxygen Transport in Tumors

Characteristics and Clinical Implications
  • Peter Vaupel
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 388)


Experimental evidence suggests that the hypoxic fraction in solid tumors may influence its growth, may increase its malignant potential, and may reduce its sensitivity towards non-surgical treatment modalities (e.g., standard irradiation, certain anticancer drugs). The role of the tumor O2 status in radio-/chemotherapy and its impact on relevant tumor biological characteristics of tumors are summarized in Table 1.


Cervical Cancer Oxygen Partial Pressure Oxygenation Status Cumulative Frequency Distribution Normal Oral Mucosa 
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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • Peter Vaupel
    • 1
  1. 1.Institute of Physiology and PathophysiologyUniversity of MainzMainzGermany

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