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The Energy Dependent Redox Responses of Heme And Copper in Cytochrome Oxidase in Rat Brain In Situ

  • A. Matsunaga
  • Y. Nomura
  • M. Tamura
  • N. Yoshimura
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 388)

Abstract

With the in vitro calibration of isolated mitochondria, it has been shown that the redox state of heme a+a3 in cytochrome oxidase depends on both mitochondrial energy state and respiratory rate, but that of copper does not (1,2, 3). This finding, however, has not been confirmed in vivo living tissues, since hemoglobin absorption masks the redox change of heme a+a3 in the visible region.

Keywords

Cytochrome Oxidase Cerebral Tissue Redox Behavior Rapid Phase Redox Level 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • A. Matsunaga
    • 1
    • 2
  • Y. Nomura
    • 1
  • M. Tamura
    • 1
  • N. Yoshimura
    • 2
  1. 1.Research Institute for Electronic ScienceHokkaido UniversitySapporoJapan
  2. 2.Department of AnesthesiologyKagoshima University School of MedicineKagoshimaJapan

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