The Effect of Capillary Blood Flow on the Oxygen Release into Rat Heart Tissue

Model Calculations with Point-like Sources Representing the Erythrocytes
  • Cees Bos
  • Louis Hoofd
  • Thorn Oostendorp
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 388)


Modelling of oxygen transport into tissue can be considered in two steps. The first step comprises the release from the oxygen carriers, the erythrocytes, in the streaming blood up to the capillary wall. The second step models the diffusional transport in the - stagnant -tissue, including the capillary wall. Many literature models only involve the second step. The first model by Krogh (1919) used the simplified geometry of a tissue cylinder around a centrally located capillary. Since, several extensions have been made to this model establishing the basis of calculation of pO2 in muscle tissue (Hoofd, 1992).


Oxygen Transport Extraction Pressure Capillary Blood Flow Source Movement Source Spacing 
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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • Cees Bos
    • 1
  • Louis Hoofd
    • 1
  • Thorn Oostendorp
    • 2
  1. 1.Department of PhysiologyUniversity of NijmegenNijmegenThe Netherlands
  2. 2.Department of Medical Physics and BiophysicsUniversity of NijmegenNijmegenThe Netherlands

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