Estimation of Cerebral Blood Volume and Transit Time in Neonates From Quick Oxygen Increases Measured by Near-Infrared Spectrophotometry
Quick oxygen increases are used to estimate the cerebral blood flow (cbf) or cerebral haemoglobin flow (cHbf) in neonates by near infrared spectrophotometry (NIRS) (Edwards et al, Skov et al., Bucher et al.). One of the essential assumptions for the correct estimation of cbf by the Fick principle is, that the time a bolus of tracer needs to pass the cerebral compartment - the so-called transit time (tt) - exceeds 6s to 8s. This paper describes a way of estimating the tt.
KeywordsCerebral Blood Flow Pulse Oximeter Cerebral Blood Volume Oxygen Index Integration Period
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