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Ascorbic Acid and Prostaglandin Synthesis

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Subcellular Biochemistry

Part of the book series: Subcellular Biochemistry ((SCBI,volume 25))

Abstract

Among the many proposed actions of ascorbic acid, the regulation of prostaglandin synthesis has not featured prominently. Yet, there has been a steady trickle of papers since the late 1970s that have provided evidence that this could be an important mechanism of action of vitamin C. This review summarizes the evidence in the hope that more investigators may become involved in this clinically important field.

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Abbreviations

ALA:

alpha-liniolenic acid

DGLA:

dihomogamma-linolenic acid

EFA:

essential fatty acid

EPA:

eicosapentaenoic acid

GLA:

gamma-linolenic acid

12-HETE:

hydroxy-eicosatetraeroic acid

PG:

prostaglandin

NSAID:

nonsteroidal anti-inflammatory drug

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Authors and Affiliations

  1. Scotia Pharmaceuticals, Woodbridge Meadows, Surrey GU1 1BA, Guildford, England

    David F. Horrobin

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  1. David F. Horrobin
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Editor information

Editors and Affiliations

  1. Institute of Zoology, University of Mainz, Mainz, Germany

    J. Robin Harris

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© 1996 Plenum Press, New York

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Horrobin, D.F. (1996). Ascorbic Acid and Prostaglandin Synthesis. In: Harris, J.R. (eds) Subcellular Biochemistry. Subcellular Biochemistry, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0325-1_6

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  • DOI: https://doi.org/10.1007/978-1-4613-0325-1_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7998-0

  • Online ISBN: 978-1-4613-0325-1

  • eBook Packages: Springer Book Archive

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