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Apoptosis in the Human Blastocyst: Role of Survival Factors

  • Conference paper
Book cover ART and the Human Blastocyst

Part of the book series: Proceedings in the Serono Symposia USA Series ((SERONOSYMP))

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Abstract

The developmental potential of human embryos following in vitro fertilization (lVF) is poor. The implantation rate of embryos transferred 2 days after IVF is only around 25% (1), resulting in low pregnancy rates (2). If embryos are cultured in vitro, approximately 50% arrest during the first 6 days (3). The reasons for this high rate of embryo loss during early development are unclear, but they could include suboptimal culture conditions, chromosomal abnormalities, inadequate oocyte maturation, disturbances in embryo—maternal dialogue, or a nonreceptive endometrium.

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Authors
  1. Kate Hardy
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  2. Sophie Spanos
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Editor information

Editors and Affiliations

  1. Colorado Center for Reproductive Medicine, Englewood, CO, 80110, USA

    David K. Gardner D.Phil.  & Michelle Lane Ph.D.  & 

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© 2001 Springer Science+Business Media New York

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Hardy, K., Spanos, S. (2001). Apoptosis in the Human Blastocyst: Role of Survival Factors. In: Gardner, D.K., Lane, M. (eds) ART and the Human Blastocyst. Proceedings in the Serono Symposia USA Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-0149-3_11

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  • DOI: https://doi.org/10.1007/978-1-4613-0149-3_11

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-6540-5

  • Online ISBN: 978-1-4613-0149-3

  • eBook Packages: Springer Book Archive

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