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Diseases of Skin

  • Chapter
Book cover Pathology of Laboratory Animals

Abstract

The skin is unique, being the largest organ of the body, with the greatest diversity of functions, as follows:

  1. 1.

    Protection. The skin is waterproof and shields the body from microbial, mechanical, actinic, and chemical insults of the environment.

  2. 2.

    Body temperature regulation. Heat loss is prevented by fat and hair coat. Conversely, heat is removed from the body through water evaporation from the epidermis and sweat glands.

  3. 3.

    Sensory perception. Receptors for heat, cold, touch, pressure, and pain are present.

  4. 4.

    Excretion. Sweat, cerumen, sebum, salts, and possibly pheromones, are secreted from appendages of the skin.

  5. 5.

    Vitamin D and melanin synthesis.

  6. 6.

    Storage of blood, water, electrolytes, fats, and vitamins.

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References

Structure and Function of Skin

  • Aoki, T. (1955) Stimulation of the sweat glands in the hairy skin of the dog by adrenaline, noradrenaline, acetylcholine, metholyl, and pilocarpine. J. Invest. Dermatol. 24:545–556.

    Article  PubMed  CAS  Google Scholar 

  • Baker, K. F. (1966) Postnatal development of the dog’s skin. Br. Vet. J. 122:344–347.

    Google Scholar 

  • Cotchin, E. and Roe, F. (1967) Pathology of Laboratory Rats and Mice. Blackwell Scientific Publications, Oxford and Edinburgh.

    Google Scholar 

  • Creed, R. F. S. (1958) The histology of mammalian skin with special reference to the dog and cat. Vet. Rec. 70:171–175.

    Google Scholar 

  • Green, E. L., Editor (1966) Biology of the Laboratory Mouse. 2nd edition, McGraw-Hill Book Co., New York.

    Google Scholar 

  • Holmes, R. A. (1960) The microscopic anatomy of the skin of mus norvegicus albinus. M.S. Thesis, Michigan State University, East Lansing.

    Google Scholar 

  • Iwabuchi, T. (1967) General sweating on the hairy skin of the dog and its mechanisms. J. Invest. Dermatol. 49:61–70.

    PubMed  CAS  Google Scholar 

  • Knölling, O. and Grav, H. (1960) Lehrbuch der histologie und vergleichenden mikroskopischen anatomie der haustiere. Paul Parey, Berlin.

    Google Scholar 

  • Leake, L. D. (1975) Comparative Histology. An Introduction to the Microscopic Structure of Animals. Academic Press, Inc., New York.

    Google Scholar 

  • Lucas, A. M. and Stettenheim, P. R. (1972) Avian Anatomy. Integument, Parts I and II. Superintendent of Documents, U.S. Government Printing Office, Washington, D.C.

    Google Scholar 

  • Maita, K. and Ishida, K. (1975) Structure and development of the perianal gland of the dog. Jpn. J. Vet. Sci. 37:349–356.

    Article  CAS  Google Scholar 

  • Montagna, W. H. (1962) The Structure and Function of Skin. 2nd Edition. Academic Press, Inc., New York.

    Google Scholar 

  • Montagna, W. H. and Parks, H. F. (1948) A histochemical study of the glands of the anal sac of the dog. Anat. Rec. 100:297–318.

    Article  PubMed  CAS  Google Scholar 

  • Nielsen, S. W. (1953) Glands of the canine skin-morphology and distribution. Am. J. Vet. Res. 14:448–454.

    PubMed  CAS  Google Scholar 

  • Rook, A. J. and Walton, G. S. (1965) Comparative Physiology and Pathology of the Skin. F. A. Davis Company, Philadelphia.

    Google Scholar 

  • Shelley, W. B. and Perry, E. T. (1956) The physiology of the apocrine (ceruminous) gland of the human ear canal. J. Invest. Dermatol. 26:13–22.

    Article  PubMed  CAS  Google Scholar 

  • Smith, E. M. and Calhoun, M. L. (1968) The Microscopic Anatomy of the White Rat. Iowa State University Press, Ames.

    Google Scholar 

  • Strickland, J. H. and Calhoun, M. L. (1963) The integumentary system of the cat. Am. J. Vet. Res. 24:1018–1029.

    PubMed  CAS  Google Scholar 

  • Trautmann, A. and Fiebiger, J. (1957) Lehrbuch der Histologi und Vergleichenden Mikroskopischen Anatomie der Haussäugetiere. Paul Parey, Berlin, 1949. (Trans, and Rev. by R. E. Habel and E. L. Biberstein, Comstock Publishers, Assoc., Ithaca).

    Google Scholar 

  • Webb, A. J. and Calhoun, M. L. (1954) The microscopic anatomy of skin of mongrel dogs. Am. J. Vet. Res. 15:274–280.

    PubMed  CAS  Google Scholar 

Tumors of Skin

  • Barthold, S. W. and Olson, C. (1974) Viral neoplasia. IX. Papova-virus-induced neoplasia. IN Handbook of Laboratory Animal Science. Vol. 2, CRC Press, Inc., Cleveland. 70–75.

    Google Scholar 

  • Billups, L. H. (1976) Naturally occurring neoplastic diseases. II. Rat. IN Handbook of Laboratory Animal Science, Vol. 3, CRC Press, Inc., Cleveland, 227–251.

    Google Scholar 

  • Billups, L. H. and Harshbarger, J. C. (1976) Naturally occurring neoplastic diseases. XI. Reptiles. IN Handbook of Laboratory Animal Science, Vol. 3, CRC Press, Inc., Cleveland, 343–356.

    Google Scholar 

  • Blackmore, D. K. (1966) The clinical approach to tumours in cage birds. I. The pathology and incidence of neoplasia in cage birds. J. Small. Anim. Pract. 7:217–223.

    Article  PubMed  CAS  Google Scholar 

  • Bostock, D. E. and Owen, L. N. (1975) Colour Atlas of Neoplasia in the Cat, Dog, and Horse. Wolfe Medical Publications, London.

    Google Scholar 

  • Briody, B. A. (1959) Response of mice to ectromelia and vaccinia viruses. Bacteriol. Rev. 23:61–95.

    PubMed  CAS  Google Scholar 

  • Burch, G. R. (1952) Canine papillomatosis in a research kennel. Southwestern Vet. 5:359–362.

    Google Scholar 

  • Christie, G. S. and Jabara, A. G. (1964a) Apocrine cystic calcinosis: The sweat gland origin of calcinosis circumscripta in the dog. Res. Vet. Sci. 5:317–322.

    Google Scholar 

  • Christie, G. S. and Jabara, A. G. (1964b) Canine sweat gland growths. Res. Vet. Sci. 5:237–244.

    Google Scholar 

  • Cockrill, J. M. and Beasley, J. N. (1975) Ultrastructural characteristics of canine transmissible venereal tumor at various stages of growth and regression. Am. J. Vet. Res. 36:677–681.

    PubMed  CAS  Google Scholar 

  • Cordy, D. R. (1967) Apocrine cystic calcinosis in dogs and its relationship to chronic renal disease. Cornell Vet. 57:107–118.

    PubMed  CAS  Google Scholar 

  • Cotchin, E. (1956) Neoplasms of the Domesticated Mammals. Commonwealth Agricultural Bureaux, England.

    Google Scholar 

  • Cotchin, E. (1960) Calcium gout (Kalkgicht) and calcinosis circumscripta in dogs. Br. Vet. J. 116:1–6.

    Google Scholar 

  • Drommer, W. and Schultz, L.-Cl. (1969) Verleichende licht- und elektronen- mikroskopische untersuchungen am ubertragbaren venerischen sarkom und histiozytom des hundes. Pathol. Vet. 6:273–286.

    Article  PubMed  CAS  Google Scholar 

  • Evans, C. A., Rashad, A. L., and Mottet, N. K. (1964) The papilloma of rabbits induced by the virus of shope: Histologic features related to amount of virus in the tumor. IN The Epidermis, Chapter XXX. Academic Press, New York, 587–600.

    Google Scholar 

  • Forbis, R., Jr. and Helwig, E. B. (1961) Pilomatrixoma (calcifying epithelioma). Arch. Dermatol. 83:606–618.

    PubMed  Google Scholar 

  • Gates, O., Warren, S., and Warvi, W. N. (1943) Tumors of sweat glands. Am. J. Pathol. 19:591–592.

    PubMed  CAS  Google Scholar 

  • Griesemer, R. A. (1976) Naturally occurring neoplastic diseases. IX. Nonhuman primates, IN Handbook of Laboratory Animal Science, Vol. 3, CRC Press, Inc., Cleveland, 309–323.

    Google Scholar 

  • Helmboldt, C. F., Wills, F. K., and Frazier, M. N. (1963) Field observations and the pathology of skin leukosis in Gallus gallus. Avian Dis. 7:402–411.

    Article  PubMed  CAS  Google Scholar 

  • Hirth, R. S., Wyand, D. S., Osborne, A. D., and Burke, C. N. (1969) Epidermal changes caused by squirrel poxvirus. J. Am. Vet. Med. Assoc. 155:1120–1125.

    PubMed  CAS  Google Scholar 

  • Hottendorf, G. H. and Nielsen, S. W. (1966) Collagen necrosis in canine mastocytomas. Am. J. Pathol. 49:501–513.

    PubMed  CAS  Google Scholar 

  • Hottendorf, G. H. and Nielsen, S. W. (1967) Pathologic survey of 300 extirpated canine mastocytomas. Zentrabl. Veterinaermed. 14:272–281.

    Article  CAS  Google Scholar 

  • Hottendorf, G. H. and Nielsen, S. W. (1968) Pathologic report of 29 necropsies on dogs with mastocytoma. Pathol. Vet. 5:102–121.

    PubMed  CAS  Google Scholar 

  • Hottendorf, G. H. and Nielsen, S. W. (1969) Canine mastocytoma—a review of clinical aspects. J. Am. Vet. Med. Assoc. 154:917–924.

    PubMed  CAS  Google Scholar 

  • Hottendorf, G. H., Nielsen, S. W., and Kenyon, A. J. (1965) Canine mastocytoma. I. Blood coagulation time in dogs with mastocytoma. Pathol. Vet. 2:129–141.

    Google Scholar 

  • Howard, E. B. and Nielsen, S. W. (1965) Neoplasia of the boxer dog. Am. J. Vet. Res. 26:1121–1131.

    PubMed  CAS  Google Scholar 

  • Howard, E. B. and Nielsen, S. W. (1969) Cutaneous histiocytomas of dogs. Natl. Cancer Inst. Monogr. No. 32, 321–327.

    PubMed  CAS  Google Scholar 

  • Howard, E. B., Nielsen, S. W., and Kenyon, A. J. (1969a) Cutaneous lymphomatosis in a boxer dog. Pathol. Vet. 6:76–85.

    Article  PubMed  CAS  Google Scholar 

  • Howard, E. B., Sawa, T. R„ Nielsen, S. W., and Kenyon, A. J. (1969b) Mastocytoma and gastroduodenal ulceration. Gastric and duodenal ulcers in dogs with mastocytoma. Pathol. Vet. 6:146–158.

    Article  PubMed  CAS  Google Scholar 

  • Hulett, R. M. (1958) Trichomatrioma. Arch. Dermatol. 77:285–296.

    CAS  Google Scholar 

  • Jackson, C. (1936) The incidence and pathology of tumours of domesticated animals in South Africa. A study of the onderstepoort collection of neoplasms with special reference to their histopathology. Onderstepoort J. Vet. Sci. Anim. Ind. 6:3–460.

    Google Scholar 

  • Jakowski, R. M. and Helmboldt, C. F. (1976) Naturally occurring neoplastic diseases. X. Domestic fowl, in Handbook of Laboratory Animal Science, Vol. 3, CRC Press, Inc. Cleveland, 325–342.

    Google Scholar 

  • Jones, S. R. (1976) Naturally occurring neoplastic diseases. I. Mouse, IN Handbooks of Laboratory Animal Science, Vol. 3, CRC Press, Inc. Cleveland, 221–225.

    Google Scholar 

  • Krook, L. (1954) A statistical investigation of carcinoma in the dog. Acta. Pathol. Microbiol. Scand. 35:407–422.

    Article  PubMed  CAS  Google Scholar 

  • Langham, R. F. and Schirmer, R. G. (1968) Value of histopathologic examination in diagnosis of dermatologic disorders of small animals. J. Am. Vet. Med. Assoc. 153:1754–1758.

    PubMed  CAS  Google Scholar 

  • Lapen, R. F., Piper, R. C., and Kenzy, S. G. (1970) Cutaneous changes associated with Marek’s disease of chickens. J. Natl. Cancer Inst. 45:941–950.

    PubMed  CAS  Google Scholar 

  • Larsson, B. (1956) Statistical analyses of cutaneous tumors in dogs. Nord. Veterinaermed. 8:130–139.

    Google Scholar 

  • Liu, S.-K. and Hohn, B. R. (1968) Squamous cell carcinoma of the digit of the dog. J. Am. Vet. Med. Assoc. 153: 411–424.

    PubMed  CAS  Google Scholar 

  • Mills, J. H. L. and Nielsen, S. W. (1967a) Canine haemangiopericytomas. A survey of 200 tumors. J. Small Anim. Pract. 8:599–604.

    Article  PubMed  CAS  Google Scholar 

  • Mills, J. H. L. and Nielsen, S. W. (1967b) Age, breed, and sex distribution in Connecticut dogs. J. Am. Vet. Assoc. 151:1079–1083.

    CAS  Google Scholar 

  • Mulligan, R. M. (1949) Neoplasms of the Dog. Williams and Wilkins, Baltimore.

    Google Scholar 

  • Mulligan, R. M. (1961) Melanoblastic tumors in the Dog. Am. J. Vet. Res. 22:345–351.

    PubMed  CAS  Google Scholar 

  • Nielsen, S. W. (1952) Clinical aspects of mastocytoma in dogs. Frequency, regional involvement, metastasis, recurrence, and differential clinical and pathological diagnosis. Proc. 89th Ann. Meet. Am. Vet. Med. Assoc., 212–217.

    Google Scholar 

  • Nielsen, S. W. (1976) Canine and feline neoplasia. IN Handbooks of Laboratory Animal Science, Vol. 3, CRC Press, Inc., Cleveland, 887:943.

    Google Scholar 

  • Nielsen, S. W. and Aftosmis, J. (1964) Canine perianal gland tumors. J. Am. Vet. Med. Assoc. 144:127–135.

    PubMed  CAS  Google Scholar 

  • Nielsen, S. W. and Cole, C. R. (1958) Canine mastocytoma—a report of one hundred cases. Am. J. Vet. Res. 19:417–432.

    PubMed  CAS  Google Scholar 

  • Nielsen, S. W. and Cole, C. R. (1960) Cutaneous epithelial neoplasms of the dog. A report of 153 cases. Am. J. Vet. Res. 21:931–948.

    PubMed  CAS  Google Scholar 

  • Olson, C. (1963) Cutaneous papillomatosis in cattle and other animals. Ann. NY Acad. Sci. 108:1042–1056.

    Article  PubMed  CAS  Google Scholar 

  • Olson, R. G. and Yohn, D. S. (1974) Viral neoplasia. X. Tumor-forming poxviruses. IN Handbook, of Laboratory Animal Science. Vol. 2. CRC Press Inc., Cleveland, 76–84.

    Google Scholar 

  • Owen, L. N. (1967) Calcinosis circumscripta (calcium gout) in related Irish wolfhounds. J. Small Anim. Pract. 8:291–292.

    Article  PubMed  CAS  Google Scholar 

  • Peters, J. A. (1969) Canine mastocytoma. Excess risk as related to ancestry. J. Natl. Cancer Inst. 42:435–443.

    PubMed  CAS  Google Scholar 

  • Robinson, R. F. (1976) Naturally occurring neoplastic diseases. III. Hamster. IV. Gerbil. V. Guinea Pig, IN Handbook of Laboratory Animal Science, Vol. 3, CRC Press, Inc., Cleveland, 253–278.

    Google Scholar 

  • Rook, A. and Champion, R. H. (1963) Keratoacanthoma. Natl. Cancer Inst. Monogr. No. 10, 257–273.

    Google Scholar 

  • Rudolph, R. and Thiel, W. (1976) Pathologische anatomie und histologie von spontanen, epithelialen hauttumoren bei mastomys natalensis. Zentralbl. Veterinaermed. A 23:429–441.

    Article  CAS  Google Scholar 

  • Sandersleben, J. (1964) Gutartige epitheliale neubildungen in der haut des hundes. Zentralbl. Veterinaermed. 8:702.

    Google Scholar 

  • Schiller, A. L., Hunt, R. D., and DiGiacoma, R. (1969) Basal cell tumour in a rhesus monkey (Macaca mulatta). J. Pathol. 99:327–329.

    Article  PubMed  CAS  Google Scholar 

  • Simon, J. and Bullard, R. K. (1973) Transmissible fibroma of grey squirrels (a case report). Vet. Med. Small Anim. Clin. 68:1282–1283.

    PubMed  CAS  Google Scholar 

  • Stannard, A. A., and Pulley, L. T. (1975) Intracutaneous cornifying epithelioma (keratoacanthoma) in the dog: A retrospective study of 25 cases. J. Am. Vet. Med. Assoc. 167:385–388.

    PubMed  CAS  Google Scholar 

  • Stedham, M. A. (1976) Naturally occurring neoplastic diseases. VI. Rabbit. IN Handbook of Laboratory Animal Science, Vol. 3, CRC Press, Inc., Cleveland, 279–285.

    Google Scholar 

  • Stewart, H. L., Snell, K. C., Dunham, L. J., and Schlyen, S. M. (1959) Transplantable and Transmissible Tumors of Animals. AFIP, Washington.

    Google Scholar 

  • Taylor, D. O. N., Dorn, C. R., and Luis, O. H. (1969) Morphologic and biologic characteristics of the canine cutaneous histiocytoma. Cancer Res. 29:83–92.

    PubMed  CAS  Google Scholar 

  • Turhan, B. and Krainer, L. (1942) Bemerkungen über die sogenannten verkalkenden epitheliome der haut und ihre genese. Dermatologica. 85:73.

    Article  Google Scholar 

  • Turusov, V. S. (1973) Pathology of Tumours in Laboratory Animals. Vol. I. Tumours of the Rat. Part I, International Agency for Research on Cancer, Lyon, Sci. Publ. No. 5.

    Google Scholar 

  • Weiss, E. (1974) Tumours of the soft (mesenchymal) tissues. Bull WHO. 50:101–110.

    PubMed  CAS  Google Scholar 

  • Weiss, E. and Frese, K. (1974) Tumours of the skin. Bull. WHO. 50:79–100.

    PubMed  CAS  Google Scholar 

  • Willson, J. E. and Brown, D. E. (1974) Malignant perianal gland tumor with metastasis in a dog. J. Am. Vet. Med. Assoc. 144:389–394.

    Google Scholar 

  • Zelickson, A. S. (1963) An electron microscope study of virus-like particles in keratoacanthomas. IN Proceed. Internatl. Congress. Dermatol., Vol. I, 823–826.

    Google Scholar 

Endocrine Dermatoses

  • Amoroso, E. C. and Ebling, F. J. (1966) Allergic and endocrine dermatoses in the dog and cat. II. Hormones and skin. J. Small Anim. Pract. 7:755–775.

    Article  PubMed  CAS  Google Scholar 

  • Capen, C. C., Belshaw, B. E., Martin, S. L. (1975) Endocrine disorders. IN Textbook of Veterinary Internal Medicine—Diseases of the Dog and Cat, (S. J. Ettinger, editor) W. B. Saunders, Co. Philadelphia, Vol. 2, 1351–1452.

    Google Scholar 

  • Freudiger, U. (1959) Uber Haarschäden und Alopezien beim Hunde. Schweiz. Arch. Tierheilkd, 101:448–458.

    Google Scholar 

  • Joshua, J. O. (1958) Non-parasitic skin diseases of the dog and cat. Vet. Rec. 70:193–198.

    Google Scholar 

  • Thomsett, L. R. (1966) Allergic and endocrine dermatoses in the dog and cat. III. Endocrine disorders and hair loss in the dog. J. Small Anim. Pract. 7:777–780.

    Article  PubMed  CAS  Google Scholar 

Parasitic Diseases

  • Dikmans, G. (1948) Skin lesions of domestic animals in the United States due to nematode infestation, Cornell Vet. 38:3–22.

    PubMed  CAS  Google Scholar 

  • Flynn, R. J. (1973) Parasites of Laboratory Animals. Iowa State University Press, Ames.

    Google Scholar 

  • Foxx, T. S. and Ewing, S. A. (1969) Morphologic features, behavior, and life history of Cheyletiella yasguri. Am. J. Vet. Res. 30:269–285.

    PubMed  CAS  Google Scholar 

  • Friedman, S. and Weisbroth, S. H. (1975) The parasitic ecology of the rodent mite, Myobia musculi. II. Genetic Factors. Lab. Anim. Sci. 25:440–445.

    PubMed  CAS  Google Scholar 

  • Galton, M. (1963) Myobic mange in the mouse leading to skin ulceration and amyloidosis. Am. J. Pathol. 43:855–865.

    PubMed  CAS  Google Scholar 

  • Hirsh, D. C., Baker, B. B., Wiger, N., Yaskulski, S. G., and Osburn, B. I. (1975) Suppression of in vitro lymphocyte transformation by serum from dogs with generalized demodicosis. Am. J. Vet. Res. 36:1591–1595.

    PubMed  CAS  Google Scholar 

  • Kalkofen, U. P. and Greenberg, J. (1974) Public health implications of pulex irritans infestations of dogs. J. Am. Vet. Med. Assoc. 165:

    Google Scholar 

  • Koffman, A. M. and Viriden, P. (1949) Nagra Cheyletiella parasitivorax fall hos Katt och Kanin. Nord. Veterinaermed. 1:449–454.

    Google Scholar 

  • Levine, N. D. (1974) Diseases of laboratory animals—parasitic, IN Handbook of Laboratory Animal Science. Vol. 2, CRC Press, Inc., Cleveland, 289–327.

    Google Scholar 

  • Niggli, H. B. and Teuscher, E. (1959) Raubmilben (Cheyletiella parasitivorax) als Akzidentelle Hautparasiten bei der Katze, Schweiz. Arch. Tierheilkd. 101:107–112.

    Google Scholar 

  • Oldham, J. N. (1967) Helminths, ectoparasites and protozoa in rats and mice. IN Pathology of Laboratory Rats and Mice. Blackwell Scientific Publications, Oxford and Edinburgh, 641–679.

    Google Scholar 

  • Scot, D. W., Schultz, R. D., and Baker, E. (1976) Further studies on the therapeutic and immunologic aspects of generalized dermodectic mange in the dog. J. Am. Anim. Hosp. Assoc. 12:203–213.

    Google Scholar 

  • Soulsby, E. J. L. (1968) Helminths, Arthropods, and Protozoa of Domesticated Animals, Williams and Wilkins Company, Baltimore.

    Google Scholar 

  • Weisbroth, S. H., Friedman, S., Powell, M., and Scher, S. (1974) The parasitic ecology of the rodent mite, Myobia musculi. I. Grooming factors. Lab. Anim. Sci. 24:510–516.

    PubMed  CAS  Google Scholar 

Mycotic Diseases

  • Barsanti, J. A., Attleberger, M. H., and Henderson, R. A. (1975) Phycomycosis in a dog. J. Am. Vet. Med. Assoc. 167:293–293.

    PubMed  CAS  Google Scholar 

  • Georg, L. K. (1954) The diagnosis of ringworm in animals. Vet. Med. 49:157–166.

    Google Scholar 

  • Gierløfif, C. H. (1961) Om trichophyti, specielt hos kanin og hund. Nordisk Veterinaermed. 13:177–196.

    Google Scholar 

  • Hagen, K. W., and Gorham, J. R. (1972) Dermatomycoses in fur animals: chinchilla, ferret, mink and rabbit. Vet. Med. Small Anim. Clin. 67:43–48.

    PubMed  CAS  Google Scholar 

  • Kaplan, W., George, L. K., and Bromley, C. L. (1957) Ringworm in cats caused by microsporum gypseum. Vet. Med. 52:347–350.

    Google Scholar 

  • King, N. W. Jr. (1976) Synopsis of the pathology of new world monkeys. First Inter-American Conference on Conservation and Utilization of American Nonhuman Primates in Biomedical Research, WHO Sci. Publ. No. 317, 169–198.

    Google Scholar 

  • Nielsen, S. W. (1962) Infectious granulomas. IN E. Joest Handbuch Der Speziellen Pathologischen Anatomie Der Haustiere. Vol. 2, 3rd Edition, Paul Parey, Berlin, 632–638.

    Google Scholar 

  • Sauer, R. M. (1966) Cutaneous mucormycosis (Phycomycosis) in a squirrel (Sciurus Carolinensis), Am. J. Vet. Res. 27:380–383.

    PubMed  CAS  Google Scholar 

  • Saunders, L. Z. (1952) Cutaneous blastomycosis in the dog. North Am. Vet. 29:650–652.

    Google Scholar 

  • Schiefer, B. (1967) Pathomorphologie der systemmykosen der tieres. Gustav Fischer Verlag, Jena and München.

    Google Scholar 

  • Smith, H. A., Jones, T. C., and Hunt, R. D. (1972) Veterinary Pathology, 4th Edition. Lea and Febiger, Philadelphia.

    Google Scholar 

  • Smith, J. M. B. (1974) Diseases of Laboratory Animals—Mycotic. IN Handbook of Laboratory Animal Science, Vol. 2, CRC Press, Inc. Cleveland, 331–344.

    Google Scholar 

  • Smith, J. M. B. and Austwick, P. K. C. (1967) Fungal diseases of rats and mice. IN Pathology of Laboratory Rats and Mice. Blackwell Scientific Publications, Oxford and Edinburgh, 681–732.

    Google Scholar 

Bacterial Diseases

  • Ash, G. W. (1971) An epidemic of chronic skin ulceration in rats. Lab. Anim. Cat. 5:115–122.

    Article  CAS  Google Scholar 

  • Austin, V. H. (1975) Common skin problems in cats. Mod. Vet. Pract. 56:541–545.

    PubMed  CAS  Google Scholar 

  • Frazier, M. N., Parizek, W. J., and Garner, E. (1964) Gangrenous dermatitis of chickens, Avian Dis. 8:269–273.

    Article  Google Scholar 

  • Frye, F. L., Carney, J. D., and Laughman, W. D. (1974) Feline lepromatous leprosy. Vet. Med. Small Anim. Clin. 69:1272.

    PubMed  CAS  Google Scholar 

  • Gleiser, C. A. (1974) Diseases of laboratory animals—bacterial. IN Handbook, of Laboratory Animal Science, Vol. 2, CRC Press, Inc. Cleveland, 273–285.

    Google Scholar 

  • Hearst, B. R. (1967a) Low incidence of staphylococcal dermatitides in animals with high incidence of Staphylococcus aureus. Part I. Preliminary Study of Cats. Vet. Med. 62:475–477.

    CAS  Google Scholar 

  • Hearst, B. R. (1967b) Low incidence of staphylococcal dermatitidis in animals with high incidence of staphylococcus aureus. Part 2. Preliminary study of Dogs. Vet. Med. 62:541–542.

    CAS  Google Scholar 

  • Jennings, A. R. (1949) Feline tuberculosis. Vet. Rec. 61:380.

    Google Scholar 

  • Jones, L. D. (1956) Exudative epidermitis of pigs. Am. J. Vet. Res. 17:179–193.

    PubMed  CAS  Google Scholar 

  • Jubb, K. V. F. and Kennedy, P. C. (1963) Pathology of Domestic Animals, Vol. 2, Academic Press, New York.

    Google Scholar 

  • Kristensen, S. (1975) A study of skin diseases of dogs and cats. I. Histology of the hairy skin of dogs and cats. Nord. Veterinaermed. 27:593–603.

    CAS  Google Scholar 

  • Krogh, H. V. and Kristensen, S. (1976) A study of skin diseases in dogs and cats. II. Microflora of the normal skin of dogs and cats. Nord. Veterinaermed. 28:459–463.

    CAS  Google Scholar 

  • L’Ecuyer, C. and Jericho, K. (1966) Exudative epidermitis in pigs: Etiological studies and pathology. Can. J. Comp. Med. Vet. Sci. 30:94–101.

    PubMed  Google Scholar 

  • Lever, W. F. (1961) Histopathology of the Skin, 3rd Edition. J. B. Lippincott, Co., Philadelphia.

    Google Scholar 

  • Lindsey, J. R. and Melby, E. C., Jr. (1966) Naturally occurring primary cutaneous tuberculosis in the rhesus monkey. Lab. Anim. Care. 16:369–385.

    PubMed  CAS  Google Scholar 

  • Mebus, C. A., Underdahl, N. R. and Twiehaus, M. J. (1968) Exudative epidermitis. Pathogenesis and Pathology. Pathol. Vet. 5:146–163.

    PubMed  CAS  Google Scholar 

  • Muller, G. H. and Kirk, R. W. (1976) Small Animal Dermatology. W. B. Saunders Company, Philadelphia.

    Google Scholar 

  • Pillsbury, D. M., Shelley, W. B., and Kligman, A. M. (1961) A Manual of Cutaneous Medicine. W. B. Saunders Co., Philadelphia.

    Google Scholar 

  • Quadros, E. (1974) Furunculosis in dogs. Aetiology, pathogenesis, and treatment. A clinical study. Acta Vet. Scand. Suppl. 52.

    Google Scholar 

  • Reichenbach-Klink, H. and Elkan, E. (1965) The Principal Diseases of Lower Vertebrates. Academic Press, New York.

    Google Scholar 

  • Ribelin, W. E. and Migaki, G. (Editors) (1975) The Pathology of Fishes. University of Wisconsin Press, Madison.

    Google Scholar 

  • Robison, M. (1975) Skin granuloma of cats associated with acid-fast bacilli. J. Small. Anim. Pract. 16:563–567.

    Article  Google Scholar 

  • Ruch, T. C. (1959) Diseases of Laboratory Primates. W. B. Saunders, Philadelphia.

    Google Scholar 

  • Schiefer, B., Gee, B. R., and Ward, G. E. (1974) A disease resembling feline leprosy in western Canada. 165:1085–1087.

    CAS  Google Scholar 

  • Schwartzman, R. M. and Maguire, H. G. (1969) Staphylococcal apocrine gland infections in the dog (canine hidradenitis suppurativa). Br. Vet. J. 125:121–127.

    PubMed  CAS  Google Scholar 

  • Shults, F. S., Estes, P. C., Franklin, J. A. and Richter, C. B. (1973) Staphylococcal botryomycosis in a specific pathogen-free mouse colony. Lab. Anim. Sci. 23:36–42.

    PubMed  CAS  Google Scholar 

  • Sompolinsky, D. (1950) Impetigo contagiosa suis. Dansk Maanedsskrift Dyrlaeger. 61:401–453.

    Google Scholar 

  • Stewart, D. D., Buck, G. E., McConnell, E. E., and Amster, R. L. (1975) An epizootic of necrotic dermatitis in laboratory mice caused by Lancefield Group G Streptococci. Lab. Anim. Sci. 25:296–302.

    PubMed  CAS  Google Scholar 

  • Swerczek, T. W., Schiefer, B., and Nielsen, S. W. (1968a) Canine actinomycosis. Zentralblatt f. Vet. Med. B15:955–970.

    Google Scholar 

  • Swerczek, T. W., Schiefer, B., and Nielsen, S. W. (1968a) Canine. Nocardiosis. Zentralblatt f. Vet. Med. B15:971–978.

    Google Scholar 

  • Underdahl, N. R., Grace, P. D., and Young, G. A. (1963) Experimental transmission of exudative epidermitis of pigs. J. Am. Vet. Med. Assoc. 142:754–762.

    PubMed  CAS  Google Scholar 

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Authors
  1. Svend W. Nielsen
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Editors and Affiliations

  1. Zoological Society of San Diego, P.O. Box 551, San Diego, California, 92112, USA

    K. Benirschke M.D.

  2. 4416 Oak Hill, Rockville, Maryland, 20853, USA

    F. M. Garner D.V.M.

  3. New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts, 01772, USA

    T. C. Jones D.V.M., D.Sc.

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© 1978 Springer-Verlag New York Inc.

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Nielsen, S.W. (1978). Diseases of Skin. In: Benirschke, K., Garner, F.M., Jones, T.C. (eds) Pathology of Laboratory Animals. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-9942-4_8

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  • DOI: https://doi.org/10.1007/978-1-4612-9942-4_8

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