Treatment of Shock and Trauma States: Use of Cardiorespiratory Patterns to Define Therapeutic Goals, Predict Survival, and Titrate Therapy
For maximal effectiveness, therapy should be directed against the basic underlying pathophysiologic mechanisms and toward optimal physiologic values. Therapy should be given vigorously in the early stages where it is most effective, as no amount of belated therapy can be expected to compensate for previous failure to recognize the insidious onset of shock. The major problems are to define with precision the pathophysiologic mechanisms and the therapeutic goals so that the therapy may be given in the optimal order and be titrated to ensure maximal survival.
KeywordsCatheter Albumin Urea Dopamine Lactate
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- 1.Shoemaker, W. C. (1972). Cardiorespiratory patterns in clinical shock as physiologic criteria for therapy and early warning of death. In: Advances in Automated Analysis. Vol. 2: 15–22. Tarrytown, New York: Medical Inst.Google Scholar
- 3.Shoemaker, W. C. (1973). Pathophysiologic basis of therapy for shock and trauma syndromes. Semin. Drug Treat. 5:211.Google Scholar
- 4.Shoemaker, W. C., Boyd, D. M., Kim, S. I., Brown, R. S., Dreiling, D. A., and Kark, A. E. (1971). Sequential oxygen transport and acid-base changes after trauma to the unanesthetized patient. Surg. Gynec. Obstet. 752:1023.Google Scholar
- 5.Shoemaker, W. C., Carey, J. S., Yao, S. T., Mohr, P. A., Amato, J. J., Printen, K. J., Corley, R. D., and Monson, D. O. (1970). Hemodynamic alterations in acute cardiac tamponade after penetrating injuries of the heart. Surg. 67:754.Google Scholar
- 7.Shoemaker, W. G., Lim, L., Boyd, D. M., Corley, R. S., Reinhard, J. M., Dreiling, D. A., and Kark, A. E. (1971). Sequential hemodynamic events after trauma to the unanesthetized patient. Surg. Gynec. Obstet. 752:651.Google Scholar
- 8.Shoemaker, W. C., Montgomery, E. S., Elwyn, D. H., Levin, H., and Rosen, A. L. Early prediction of death and survival by prospective analysis of cardiorespiratory variables in postoperative shock patients. Curr. Topics Crit. Care Med. 2:44–59, 1977.Google Scholar
- 10.Shoemaker, W. C., Printen, K. J., and Amato, J. J. (1967). Hemodynamic patterns after acute anesthetized and unanesthetized trauma. Arch. Surg. 951:492.Google Scholar
- 11.Weil, M. H., and Shubin, H. (1966). Diagnosis and Treatment of Shock. Baltimore, Williams and Wilkins.Google Scholar
- 12.Wilson, R. F., Jablonski, D. V., and Thai, A. P. (1964). The usage of dibenzyline in clinical shock. Surgery 56:112.Google Scholar