Skip to main content

Weaning from Mechanical Ventilation

  • Chapter
Critical Care Medicine Manual

Abstract

Weaning from mechanical ventilation is a poorly understood and often frustrating phase of management of acute respiratory failure (ARF) [6]. With the exception of diseases known to require prolonged, uninterrupted, mechanical ventilation (MV)—i.e., severe tetanus, polyneuritis, and massive chest trauma with severe flailing—consideration should be given to weaning from MV as soon as certain simple criteria are met. These criteria are as follows: (a) vital capacity > 4–5 ml/kg, (b) inspiratory force > 10 cm H2O, \( \left( c \right)\,\,A - a{\rm{ }}{P_{{O_2}}}\; < \;350\;torr, \) (d) positive end-expiratory pressure requirement < 10 cm H2O, (e) stable cardiovascular system, (f) chest-wall flailing not severe, and (g) close supervision by experienced physicians.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Beach, T., Millen, E., and Grenvik, A. (1973). Hemodynamic response to discontinuance of mechanical ventilation. Crit. Care Med. 1:85–90.

    Article  PubMed  CAS  Google Scholar 

  2. Breivik, H., Grenvik, A., Millen, E., and Safar, P. (1973). Normalizing low arterial CO2 tension during mechanical ventilation. Chest 63:525–531.

    Article  PubMed  CAS  Google Scholar 

  3. Downs, J. B., Klein, E. F., and Desautels, D. A. (1973). Intermittent mandatory ventilation: A new approach to weaning patients from mechanical ventilation. Chest 64:331–335.

    Article  PubMed  CAS  Google Scholar 

  4. Froese, A. B., and Bryan, A. C. (1974). Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology 41:242–255.

    Article  PubMed  CAS  Google Scholar 

  5. Goldman, M. D., and Mead, J. (1973). Mechanical interaction between the diaphragm and rib cage. J. Appl. Physiol. 35:197–204.

    PubMed  CAS  Google Scholar 

  6. Hodgkin, J. E., Bowser, M. A., and Burton, G. G. (1974). Respirator weaning. Crit. Care Med. 2:96–102.

    Article  PubMed  CAS  Google Scholar 

  7. Peters, R. M., Hilberman, M., and Hogan, J. S. (1972). Objective indications for respiratory therapy in post-trauma and post-operative patients. Am. J. Surg. 124:262–269.

    Article  PubMed  CAS  Google Scholar 

  8. Pilon, R. N., and Bittar, D. A. (1973). The effect of positive end-expiratory pressure on thoracic-duct lymph flow during controlled ventilation in anesthetized dogs. Anesthesiology 39:607–612.

    Article  PubMed  CAS  Google Scholar 

  9. Pontoppidan, H., Geffin, B., and Lowenstein, E. (1973). Acute Respiratory Failure in the Adult. Boston: Little, Brown.

    Google Scholar 

  10. Suwa, K., Geffin, B., Pontoppidan, H., and Bendixen, H. H. (1968). A nomogram for dead-space requirement during prolonged artificial ventilation. Anesthesiology 29:1206–1210.

    Article  PubMed  CAS  Google Scholar 

  11. Trichet, B., Falke, K., and Togot, A. (1975). The effect of preexisting pulmonary vascular disease on the response to mechanical ventilation with PEEP following open-heart surgery. Anesthesiology 42:46–57.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1978 Springer-Verlag New York Inc.

About this chapter

Cite this chapter

Pontoppidan, H., Browne, D.R.G. (1978). Weaning from Mechanical Ventilation. In: Critical Care Medicine Manual. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-9932-5_6

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-9932-5_6

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-9934-9

  • Online ISBN: 978-1-4612-9932-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics