A method to identify and treat reversible ischemic alterations of brain tissue
Inadequate perfusion to a portion of the brain results in neurologic deficit which appears to be primarily due to hypoxia.(4) If cerebral hypoxia, ischemia, or a combination of these lead only to temporary or slight neurologic deficit, reconstructive surgery of cerebral arteries is an accepted procedure. (6) There is, however, considerable pessimism regarding the value of surgery in patients with severe fixed neurologic deficit following stroke.(6,7) In such patients we really cannot predict whether their neurologic deficit results from reversible or irreversible hypoxia and/or ischemic alteration. We, therefore, have approached this problem by studying the effects of hyperbaric oxygen (HO) treatment and subsequently of an extra- intracranial arterial bypass (EIAB) on patients suffering from chronic cerebral ischemia.
KeywordsNeurologic Deficit Hyperbaric Oxygen Superficial Temporal Artery Hyperbaric Oxygen Therapy Electrical Brain Activity
Unable to display preview. Download preview PDF.
- 2.Holbach KH, Wassmann H, Hohelüchter KL, Jain KK: Differentiation between reversible and irreversible poststroke changes in brain tissue and its relevance for cerebrovascular surgery. Surg Neurol (in press)Google Scholar
- 3.Holbach KH, Caroli A: Oxygen tolerance and the oxygenation state of the injured human brain. In Trapp WG, Banister EW, Davison AJ, Trapp PA (eds): Fifth International Hyperbaric Congress Proceedings 1973. Burnaby, Canada, Simon Fraser University, 1974, pp 350–361.Google Scholar
- 4.Ingvar DH: The pathophysiology of the stroke related to findings in EEG and to measurements of regional cerebral blood flow. In Engel A, Larsson T (eds): Stroke. Thüle International Symposia. Stockholm, Nordiska Bokhandelns Förlag, 1967Google Scholar
- 6.Reichman OH, Davis DO, Roberts TS, Satovick RM: Anastomosis between STA and cortical branch of MCA for the treatment of occlusive cerebrovascular disease. In Mérei FT (eds): Reconstructive Surgery of Brain Arteries. Budapest, Académiai Kiadó, 1974, pp 201–218Google Scholar
- 7.Vollmar J: Rekonstruktive Chirurgie der Arterien. Stuttgart, Thieme, 1975, pp 300–345Google Scholar
- 8.Yasargil GM: Microsurgery Applied to Neurosurgery. Stuttgart, Thieme, 1969Google Scholar