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Cryosurgery in Dermatology

  • Setrag A. Zacarian

Abstract

Nearly one-half of all integumentary disorders that confront the dermatologist necessitate the use of some form of physical modality for effective management. Liquid nitrogen has been the ideal refrigerant. It is readily available, nonexplosive, and extremely cold, having a boiling point of -196 C. This last characteristic is most essential if one is to treat malignant tumors of the skin. Dry ice (CO2,-78.5 C) and instruments that employ liquid nitrous oxide (LN2O,-89.5 C) are effective only for the treatment of benign and precancerous growths, including the management of acne. The anatomic depth of skin cancers precludes coolants with a low boiling point (Table 26-1). The cryogen must be sufficiently cold, as with liquid nitrogen, to overcome the microcirculatory barrier of the integument and allow the ice front to develop and extend into the subcutaneous tissue and beyond.

Keywords

Skin Cancer Basal Cell Carcinoma Acne Scar Medial Canthus Seborrheic Keratose 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1978

Authors and Affiliations

  • Setrag A. Zacarian

There are no affiliations available

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