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Abstract

In this chapter we will review some of the information available concerning the response of cells to radiation and how this information helps to explain the response of normal tissues and tumors to radiation.

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References

  1. Catterall M: Clinical experience with fast neutrons from the Hammersmith cyclotron. Eur J Cancer 7: 227, 1971

    PubMed  CAS  Google Scholar 

  2. Churchill-Davidson I, Sanger C, Thomlinson RH: High pressure oxygen and radiotherapy. Lancet 1: 1091, 1955

    Article  Google Scholar 

  3. Dalrymple GV, Gaulden ME, Kollmorgen GM et al: Medical Radiation Biology. Philadelphia, Saunders, 1973

    Google Scholar 

  4. Deschner EE, Gray LH: Influence of oxygen tension on x-ray induced chromosomal damage in Ehrlich ascites tumor cells irradiated in vitro and in vivo. Radiat Res 11: 115, 1959

    Article  PubMed  CAS  Google Scholar 

  5. Dewey DL: The x-ray sensitivity of Serratia marcescens. Radiat Res 19: 64, 1963

    Article  PubMed  CAS  Google Scholar 

  6. Elkind MM, Sutton H: X ray damage and recovery in mammalian cells in culture. Nature 184: 1293, 1959

    Article  PubMed  CAS  Google Scholar 

  7. Elkind MM, Sutton H: Radiation response of mammalian cells grown in culture. Radiat Res 13: 556, 1960

    Article  PubMed  CAS  Google Scholar 

  8. Ellis F: Dose, time, and fractionation. A clinical hypothesis. Clin Radiol 20: 1, 1969

    Article  PubMed  CAS  Google Scholar 

  9. Freifelder D: Lethal changes in bacteriophage DNA produced by x-rays. Radiat Res (Suppl) 6: 80, 1966

    Article  Google Scholar 

  10. Gray LH, Conger AD, Eibert M, et al: The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy. Br J Radiol 26: 638, 1953

    Article  PubMed  CAS  Google Scholar 

  11. Hewitt HB: Radiation Effects in Physics, Chemistry, and Biology. Amsterdam, North-Holland, 1963

    Google Scholar 

  12. Johns HE, Cunningham JR: The Physics of Radiology. Springfield, Ill, Thomas, 1969

    Google Scholar 

  13. Kaplan HS: Enzymatic repair of radiation-induced strand breakage in cellular DNA and its chemical inhibition. Radiology 105: 121, 1972

    PubMed  CAS  Google Scholar 

  14. Kunkler PB, Henk JM, Shah NK, et al: Radiotherapy and hyperbaric oxygen in malignant tumours of the oral cavity and oropharynx with lymph node metastases. Gann Monograph No. 9. Tokyo, Maruzen, 1970

    Google Scholar 

  15. Lawson RC, Watt DE: The LET distribution of the recoil proton dose from DD and DT neutrons. Phys Med Biol 22: 217, 1967

    Article  Google Scholar 

  16. Lockart RZ, Elkind MM, Moses WB: Radiation response of mammalian cells grown in culture. II. Survival and recovery characteristics of several subcultures of HeLa S 3 cells after x-irradiation. J Natl Cancer Inst 27: 1393, 1961

    PubMed  Google Scholar 

  17. Puck TT, Marcus PI: Action of x rays on mammalian cells. J Exp Med 103: 653, 1956

    Article  PubMed  CAS  Google Scholar 

  18. Sinclair WK: X-ray-induced heritable damage (small colony formation) in cultured mammalian cells. Radiat Res 21: 584, 1964

    Article  PubMed  CAS  Google Scholar 

  19. Suit HD: Radiation biology. A basis for radiotherapy. In Fletcher GH (ed): Textbook of Radiotherapy. Philadelphia, Lea and Febiger, 1966

    Google Scholar 

  20. Tessman I: Mutagenesis in phages ø-X 174 and T4 and properties of the genetic material. Virology 9: 375, 1959

    Article  CAS  Google Scholar 

  21. Tessman I, Tessman ES, Stent GS: The relative radiosensitivity of bacteriophages S13 and Ts. Virology 4: 209, 1957

    Article  PubMed  CAS  Google Scholar 

  22. Van den Brenk HAS, Madigan JP, Kerr RC: Experience in Melbourne with the use of hyperbaric oxygen combined with megavoltage radia tion in 614 cases of advanced malignant disease. In Vaeth JM (ed): Frontiers of Radiation Therapy and Oncology. New York, Karger, 1968

    Google Scholar 

  23. Whitmore GF, Till JE: Quantitation of cellular radiobiological responses. Ann Rev Nucl Med 14: 347, 1964

    Article  CAS  Google Scholar 

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© 1978 Springer-Verlag New York Inc.

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Davis, L.W. (1978). Radiobiology. In: Goldschmidt, H. (eds) Physical Modalities in Dermatologic Therapy. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-6259-6_2

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  • DOI: https://doi.org/10.1007/978-1-4612-6259-6_2

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-6261-9

  • Online ISBN: 978-1-4612-6259-6

  • eBook Packages: Springer Book Archive

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