Characterization of the Myeloma Colony-Forming Cell

  • Anne W. Hamburger
  • Mary B. Kim
  • Sydney E. Salmon
Conference paper
Part of the Experimental Hematology Today book series (HEMATOLOGY, volume 1979)


Multiple myeloma has served as a model neoplasm in both mouse and man (21). Studies of myeloma immunoglobulin synthesis and metabolism have been applied to quantitate the total-body number of myeloma cells and to follow changes in tumor mass with treatment. Such serial tumor kinetic studies, and those of the tritiated thymidine labeling index of the tumor, have provided insights on the kinetics of growth and regression of myeloma and on approaches to treatment (21). Such studies, however, did not directly assess the clonigenic tumor cells, the cells that provide the basic renewal system of the tumor.


Multiple Myeloma Conditioned Medium Plasma Cell Bone Marrow Cell Colony Formation 
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Copyright information

© Springer-Verlag New York Inc. 1979

Authors and Affiliations

  • Anne W. Hamburger
  • Mary B. Kim
  • Sydney E. Salmon

There are no affiliations available

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