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The Meconium Aspiration Syndrome

  • Jean F. Hobbs
  • Arthur I. Eidelman

Abstract

Aspiration of meconium-stained amniotic fluid during the birth process is a common event that can have catastrophic results. In fact, meconium aspiration syndrome has emerged as a leading cause of death in the neonatal period, with a mortality rate in the term infant as high as 20 times that of all other causes combined (22). Moreover, the impact on infant and family of the prolonged hospitalization, complications, and sequelae of the neonatal disease can be enormous and devastating.

Keywords

Amniotic Fluid Apgar Score Fetal Heart Rate Delivery Room Endotracheal Suction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Avery, M.E., Fletcher, B.D.: The Lung and Its Disorders in the Newborn infant, 3rd Ed. Philadelphia: W. B. Saunders Co., 1974.Google Scholar
  2. 2.
    Bartlett, R.H., Gazzaniga, A.B., Jeffries, M.R., et al.: Extracorporeal membrane oxygenation (ECMO); cardio-pulmonary support in infancy. Trans. Am. Soc. Artif. Intern, Organs 22:80, 1976.Google Scholar
  3. 3.
    Bryan, C.S.: Enhancement of bacterial infection by meconium. John Hopkins Med. J. 121:9, 1967.Google Scholar
  4. 4.
    Burke-Strickland, M., Edwards, N.B.: Meconium aspiration in the newborn. Minn. Med. 56:1031, 1973.PubMedGoogle Scholar
  5. 5.
    Carson, B.S., Losey, R.W., Bowes, W.A., Simmons, M.A.: Combined obstetric and pediatric approach to prevent meconium aspiration syndrome. Am. J. Obstet. Gynecol. 126:712, 1976.PubMedGoogle Scholar
  6. 6.
    Cordero, L., Hon, E.: Neonatal bradycardia following nasopharyngeal stimulation. J. Pediatr. 78:441,1971.PubMedCrossRefGoogle Scholar
  7. 7.
    Fox, W.W., Berman, L.S., Downes, J.J., Peckham, G.J.: The therapeutic application of end-expiratory pressure in the meconium aspiration syndrome. Pediatrics 56:214, 1975.PubMedGoogle Scholar
  8. 8.
    Fox, W.W., Gewitz, M.H., Dinwiddie, R., et al.: Pulmonary hypertension in the perinatal aspiration syndromes. Pediatrics 59:205, 1977.PubMedGoogle Scholar
  9. 9.
    Frantz, I.D., Wang, N.S., Thach, B.T.: Experimental meconium aspiration: Effects of glucocorticord treatment. J. Pediatr. 86:438, 1975.PubMedCrossRefGoogle Scholar
  10. 10.
    Goetzman, B.W., Sunshine, P., Johnson, J.D., et al.: Neonatal hypoxia and pulmonary vasopasm: Response to tolazoline. J. Pediatr. 89:617, 1976.PubMedCrossRefGoogle Scholar
  11. 11.
    Gooding, C.A., Gregorp, G.A.: Roentgenographic analysis of meconium aspiration of the newborn. Radiology 100:131, 1971.PubMedGoogle Scholar
  12. 12.
    Gooding, C.A., Gregory, G.A., Taber, P., Wright, R.R.: An Experimental model for the study of meconium aspiration of the newborn. Radiology 100:137, 1971.PubMedGoogle Scholar
  13. 13.
    Goodlin, R.C.: Meconium aspiration. Obstet. Gynecol. 32:94, 1968.PubMedGoogle Scholar
  14. 14.
    Gregory, G.A., Gooding, C.A., Phibbs, R.H., Tooley, W.H.: Meconium aspiration in infants—a prospective study. J. Pediatr. 85:848, 1974.PubMedCrossRefGoogle Scholar
  15. 15.
    Hobel, C.J.: Intrapartum clinical assessment of fetal distress. Am. J. Obstet. Gynecol. 110:336, 1971.PubMedGoogle Scholar
  16. 16.
    Kandall, S.B., Albin, S., Gartner, L.M., et al.:The narcotic dependent mother: fetal and neonatal consequences. Early Human Development, 1/2: 159, 1977.PubMedCrossRefGoogle Scholar
  17. 17.
    Leake, R.D., Gunther, R., Sunshine, P.: Perinatal aspiration syndrome: its association with intrapartum events and anesthesia. Am. J. Obstet. Gynecol. 118:271, 1974.PubMedGoogle Scholar
  18. 18.
    Miller, F.C., Sacks, D.A., Yeh, S., et al.: Significance of meconium during labor. Am. J. Obstet. Gynecol. 122:573, 1975.PubMedGoogle Scholar
  19. 19.
    Peterson, H.G., Pendleton, M.E.: Contrasting roentgenographic pulmonary patterns of the hyaline membrane and fetal aspiration syndromes. Am. J. Roentgen. Radium Ther. Nucl. Med. 74:800, 1955.Google Scholar
  20. 20.
    Rememteria, J.L., Nunag, N.N.: Narcotic withdrawal in pregnancy: Stillbirth incidence with a case report. Am. J. Obstet. Gynecol. 116:1152, 1973.Google Scholar
  21. 21.
    Schaffer, A.J., Avery, M.E.: Diseases of the newborn, 3rd Ed. Philadelphia, W.B. Saunders Co., 1971.Google Scholar
  22. 22.
    Ting, P., Brady, J.P.: Tracheal suction in the meconium aspiration. Am. J. Obstet. Gynecol. 122:767, 1975.PubMedGoogle Scholar
  23. 23.
    Vidyasagar, D., Yeh, T.F., Harris, V., Pildes, R.S.: Assisted ventilation in infants with meconium aspiration syndrome. Pediatrics 56:208, 1975.PubMedGoogle Scholar
  24. 24.
    Yeh, T.F., Srinivasan, G., Harris, V., Pildes, R.S.: Hydrocortisone therapy in meconium aspiration syndrome: a controlled study. J. Pediatr. 90:140, 1977.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1979

Authors and Affiliations

  • Jean F. Hobbs
  • Arthur I. Eidelman

There are no affiliations available

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