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Circulating Immune Complexes in Cancer

  • Chapter
Cancer Markers

Part of the book series: Contemporary Biomedicine ((CB,volume 1))

Abstract

The identification of tumor markers by immunological means holds considerable promise for diagnostic applications because of the specificity and sensitivity of the assays available (Robins and Baldwin, 1977). Even more pertinent are those tumor markers that are immunogenic in the tumor-bearing individual since their interaction with the immunological network of the host should lead to the induction of specific immune responses. This type of approach excludes products such as alphafetoprotein and carcinoembryonic antigen, which have been identified primarily by the use of appropriately absorbed antisera produced in xenogeneic hosts. Nevertheless there is considerable evidence, especially from experimental animal studies, that some oncofetal antigens are immunogenic in the tumor-bearing host (Baldwin et al., 1974; Coggin and Anderson, 1974; Chism et al., 1978; Rees et al., 1979).

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Author information

Authors and Affiliations

  1. Cancer Research Campaign Laboratories, University of Nottingham, University Park, Nottingham, UK

    R. W. Baldwin & R. A. Robins

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  1. R. W. Baldwin
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  2. R. A. Robins
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Editors and Affiliations

  1. Department of Pathology, University of California Medical School, San Diego, La Jolla, California, USA

    Stewart Sell

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Baldwin, R.W., Robins, R.A. (1980). Circulating Immune Complexes in Cancer. In: Sell, S. (eds) Cancer Markers. Contemporary Biomedicine, vol 1. Humana Press. https://doi.org/10.1007/978-1-4612-6117-9_19

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  • DOI: https://doi.org/10.1007/978-1-4612-6117-9_19

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-4612-6119-3

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