Abstract
The detection and diagnosis of cancer is dependent upon the ability to discriminate between normal and neoplastic tissues. At present, this determination relies upon the recognition of abnormal morphologic features associated with neoplasia. The utilization of specific biochemical differences between normal and neoplastic tissues in the development of highly sensitive assays might yield definitive methods for the early detection of tumors. Furthermore, specific biochemical differences may be exploited for preventive and/ or curative measures. These concepts, coupled with the recent advances in the field of immunochemical analysis, have made the search for tumor-specific antigens of great interest.
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Gold, D.V., Goldenberg, D.M. (1980). Antigens Associated with Human Solid Tumors. In: Sell, S. (eds) Cancer Markers. Contemporary Biomedicine, vol 1. Humana Press. https://doi.org/10.1007/978-1-4612-6117-9_13
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