Abstract
It is likely, depending on age and still limited information, that high-density lipoprotein (HDL) levels predict coronary heart disease (CHD) risk probably as well and possibly better than total serum cholesterol (TSC) and, certainly, that their combination permits more powerful prediction than either measurement alone (Kannel et al. 1979). The correlation between TSC and low-density lipoprotein (LDL) is very high so that TSC level measures the atherogenic potential of LDL. Since there is also much evidence that HDL is causally related to atherosclerosis as a protective factor, the balance of LDL and HDL as reflected by their serum levels is likely to be a key element in atherosclerosis prevention.
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References
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© 1980 Springer-Verlag New York Inc.
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Epstein, F.H. (1980). Role of HDL in Individual Prediction and Community Prevention of Coronary Heart Disease. In: Gotto, A.M., Smith, L.C., Allen, B. (eds) Atherosclerosis V. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-6071-4_95
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DOI: https://doi.org/10.1007/978-1-4612-6071-4_95
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