Biochemical Studies on Permeability and the Interaction Between Blood Constituents and Arterial Components in Atherosclerosis
It is now accepted that large amounts of plasma low density lipoprotein (LDL), and cholesterol ester which must be derived from it, accumulate in atherosclerotic lesions, but it is not clear if this is the result of increased endothelial permeability or of increased retention within the intima. In this paper I will try to draw together some of the available biochemical evidence.
KeywordsEvans Blue Endothelial Permeability Fatty Streak Internal Elastic Lamina Mural Thrombus
Unable to display preview. Download preview PDF.
- Fry DL (1973) Responses of the arterial wall to certain physical factors. In: Atherogenesis: Initiating factors. Ciba Foundation Symposium (New Series) 12: 93Google Scholar
- Smith EB (1974) The relationship between plasma and tissue lipids in human atherosclerosis. Advan Lipid Res 12: 1Google Scholar
- Smith EB (1980) Transport of macromolecules across the artery wall. This volumeGoogle Scholar
- Smith EB, Craig IB, Dietz HS (1978) Factors influencing accumulation and destruction of lipoprotein in atherosclerotic lesions. In: Carlson LA, Paoletti R, Sirtori CR, Weber G (eds) International Conference on Atherosclerosis, Raven Press, New York, p 49Google Scholar