Abstract
The aim of drug treatment of hyperlipidaemia is long-term prevention of atherosclerosis in most cases. This implies that the drug treatment should (l) effectively reduce atherogenic i.e. very low (VLDL) and low (LDL) density lipoprotein levels, (2) have few side effects and (3) should be well tolerated and convenient to use. Available serum lipoprotein-lowering drugs do not fulfull these criteria. For example clofibrate has a poor LDL cholesterol lowering effect and might cause gall stones. Cholestyramine is in the long run often inconvenient to take and causes in 25% of cases severe constipation. Nicotinic acid may cause flushing even during continuous treatment, etc.
Supported by grants from the Swedish Medical Research Council (19X-204)
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Olsson, A.G. (1980). New Drug Treatments in Hyperlipidaemia. In: Gotto, A.M., Smith, L.C., Allen, B. (eds) Atherosclerosis V. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-6071-4_18
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DOI: https://doi.org/10.1007/978-1-4612-6071-4_18
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