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Drugs, Birth, and Ethics

  • Yvonne Brackbill
Chapter
Part of the Contemporary Issues in Biomedicine, Ethics, and Society book series (CIBES)

Abstract

When fetal organs are developing, exposure to many drugs and other substances may produce behavioral, neurological, and structural changes. These agents are called teratogens when they produce physical changes and behavioral teratogens when they produce behavioral changes with or without accompanying physical changes. Figure 1 shows, for a rat fetus, the limited periods during embryogenesis when it is susceptible to physical deformity and the longer period, preceding and following birth, when the animal is vulnerable to central nervous system damage. In human beings, the period of vulnerability to central nervous system damage from exposure to drugs and chemicals lasts much longer. Even after birth, important areas of brain are growing and differentiating at a rapid rate and are still, therefore, especially vulnerable to damage. It has been estimated that the “growth spurt” in the cerebellum lasts for about 18 months, and that in the hippocampus, for about 4.5 years.

Keywords

Private Patient Fiduciary Duty Central Nervous System Damage Central Nervous System Dysfunction Fetal Organ 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Gottlieb, G., ed., Studies on the Development of Behavior and the Nervous System, vol. 4, Early Influences, Academic, New York (1976).Google Scholar
  2. Mofenson, H. C., J. Greensher, and R. Horowitz, Hazards of Maternally Administered Drugs, Clin. Toxicol. 7, 59 (1974).CrossRefGoogle Scholar
  3. Schardein, J. L., Drugs as Teratogens, Chemical Rubber Co., Cleveland, 1976.Google Scholar
  4. Shepard, T. H., Catalog of Teratogenic Agents, 2nd ed., The Johns Hopkins University Press, Baltimore, 1976.Google Scholar
  5. Stewart, R. B., L. E. Cluff, and J. R. Philp, eds., Drug Monitoring: A Requirement for Responsible Drug Use, Baltimore, Williams & Wilkins, 1977.Google Scholar
  6. Warkany, J., Congenital Malformation, Yearbook Medical, Chicago, 1975.Google Scholar
  7. Wilson, J. G., and F. C. Fraser, eds., Handbook of Teratology, vol. 4, Plenum, New York, 1977.Google Scholar

Copyright information

© Humana Press Inc. 1980

Authors and Affiliations

  • Yvonne Brackbill

There are no affiliations available

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