Connective Tissues and the Mechanical Behavior of Lungs

  • Gordon L. Snider


It has been known for more than 150 years (1) that the lungs have elastic behavior; beginning with Orsos’ 1907 (2) classic description of normal and emphysematous lungs, there has been an ever increasing body of knowledge on the anatomic distribution of the connective tissues in the lungs. Histologic, ultrastructural, biochemical, and physiologic studies in the past 20 years on human lung disease and experimental models of lung disease have provided important new insights. Although much has been learned of the relation between the static mechanical properties of the lungs and the nature and disposition of their framework, there are still many unanswered questions regarding the role of some of the components of the connective tissues and the matrix in which they reside.


Lung Volume Elastic Fiber Transpulmonary Pressure Interstitial Pulmonary Fibrosis Lung Collagen 
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© Springer-Verlag New York, Inc. 1981

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  • Gordon L. Snider

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