Abstract
In their original studies in man, Smyth et al. (1) found that when i.v. phenylephrine [an alpha- agonist with no direct cardiac effects (2)] was used to increase arterial pressure, there was a linear relationship between systolic pressure and the pulse interval. However, when they used i.v. angiotensin II to increase arterial pressure, they observed an initial increase in pulse interval as arterial pressure increased, but “later points in the response…tended to depart from the regularly linear relation.”
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References
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© 1981 Springer-Verlag New York Inc.
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Lumbers, E.R., Potter, E.K., McCloskey, D.I., Ismay, M.J., Lee, W.B., Stevens, A.D. (1981). The Effects of Intravenous Angiotensin II on the Cardiac Baroreceptor Reflex. In: Laragh, J.H., Bühler, F.R., Seldin, D.W. (eds) Frontiers in Hypertension Research. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5899-5_91
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DOI: https://doi.org/10.1007/978-1-4612-5899-5_91
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