Position Paper: Dietary Sodium and Human Hypertension

  • George Pickering

Abstract

Albutt (1) defined his hyperpiesis, which we now term essential hypertension, as “a malady in which at or towards middle life blood pressure rises excessively”—a definition that has never been improved. The cause of this excessive rise is the outstanding problem concerning the malady. Two main possibilities exist: The cause may be genetic or environmental. Of these, the environmental hypothesis is much more attractive because it suggests possibilities for prevention and treatment. Up to now, no environmental factor of significance other than overnutrition has been identified in Western societies. Persons whose blood pressure tends to rise fastest in middle age also tend to put on weight (2). Conversely, weight reduction in the obese usually leads to a fall of arterial pressure (3).

Keywords

Filtration Sodium Chloride Diarrhea Cardiol Renin 

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References

  1. 1.
    Allbutt TC (1915) Diseases of the arteries, including angina pectoris. Macmillan, LondonGoogle Scholar
  2. 2.
    Harlan WR, Oberman A, Mitchell RE, et al (1973) A thirty year study of blood pressure in a white male cohort. In: Onesti G, Kim KE, Moyer JHGoogle Scholar
  3. 3.
    Reisin E, Abel R, Modan M, et al (1978) The effect of weight loss without salt restriction on the reduc¬tion of blood pressure in overweight hypertensive patients. N Engl J Med 298: 1PubMedCrossRefGoogle Scholar
  4. 4.
    Hamilton M, Pickering GW, Roberts JAF, et al (1954) The aetiology of essential hypertension: I. The arterial pressure in the general population. Clin Sci Mol Med 13: 11Google Scholar
  5. 5.
    Zinner SH, Levy PS, Kass EH (1971) Familial aggregation of blood pressure in childhood. N Engl J Med 284: 402CrossRefGoogle Scholar
  6. 6.
    Weitz W (1923) Zur Ätiologie der genuinen oder vasculären Hypertension. Z Klin Med 96: 151Google Scholar
  7. 7.
    Platt R (1963) Heredity and hypertension. Lancet 1: 899PubMedCrossRefGoogle Scholar
  8. 8.
    Guyton AC (1977) Personal views on mechanisms of hypertension. In: Genest J, Koiw G, Kuchel O (eds) Hypertension. McGraw-Hill, New YorkGoogle Scholar
  9. 9.
    Shaper AG (1967) Blood pressure studies in East Africa. In: Stamler J, Stamler R, Pullman TN (eds) Epidemiology of hypertension. Grune & Stratton, New YorkGoogle Scholar
  10. 10.
    Prior AM, Evans JG, Harvey HP, et al (1968) Sodium intake and blood pressure in two Polynesian populations. N Engl J Med 279: 515PubMedCrossRefGoogle Scholar
  11. 11.
    Beaglehole R, Salmond CE, Hooper A, et al (1977) Blood pressure and social interaction in Tokelauan migrants in New Zealand. J Chronic Dis 30: 803PubMedCrossRefGoogle Scholar
  12. 12.
    Dahl LK, Love RM (1954) Evidence for relationship between sodium (chloride) intake and human hypertension. Arch Intern Med 94: 525Google Scholar
  13. 13.
    Dahl LK, Love RM (1961) Possible risk of chronic excess salt consumption in the pathogenesis of essential hypertension. Am J Cardiol 8: 571CrossRefGoogle Scholar
  14. 14.
    Miall WE (1959) Follow-up study of arterial pressure in the population of a Welsh mining valley. Br Med J 2: 1204PubMedCrossRefGoogle Scholar
  15. 15.
    Oldham PD, Pickering GW, Roberts JAF, et al (1960) The nature of essential hypertension. Lancet 1: 1085PubMedCrossRefGoogle Scholar
  16. 16.
    Dawber TR, Kannel WB, Kagan A, et al (1967) Environmental factors in hypertension. In: Stamler J, Stamler R, Pullman TN (eds) Epidemiology of hypertension. Grune & Stratton, New YorkGoogle Scholar
  17. 17.
    Thomas GW, Ledingham JGG, Beilin LJ, et al (1978) Reduced renin in hypertension. Kidney Int 13: 513PubMedCrossRefGoogle Scholar
  18. 18.
    Simpson FO, Waal-Manning HJ, Bolli P, et al (1978) Relationship of blood pressure to sodium excretion in a population survey. Clin Sci Mol Med 55: 373Google Scholar
  19. 19.
    Bing RF, Thurston H, Swales JD (1979) Salt intake and diuretic treatment of hypertension. Lancet 2: 121PubMedCrossRefGoogle Scholar
  20. 20.
    Widal F (1903) Role du chlorure de sodium dans la pathogénie de certains oedèmes britiques. La Semaine Medicale 23: 199Google Scholar
  21. 21.
    Ambard L, Beaujard E (1904) Causes de l’hypertension arterielle. Archives Generales Medicine 1: 520Google Scholar
  22. 22.
    Allen FM, Sherrill JW (1922) The treatment of arterial hypertension. J Metabol Res 2: 429Google Scholar
  23. 23.
    Volhard F (1931) Nieren und Ableitende Harnwege. In: von Bergmann G, St Staehelin R (eds) Handbuch der Inneren Medizin, Vol 6. Springer, Berlin, p. 1Google Scholar
  24. 24.
    Kempner W (1948) Treatment of hypertensive vascular disease with rice diet. Am J Med 4: 545PubMedCrossRefGoogle Scholar
  25. 25.
    Watkin DM, Froeb HF, Hatch FT, et al (1959) Effects of diet in essential hypertension. Am J Med 26: 428Google Scholar
  26. 26.
    Parijs J, Joosens JV, van der Linden L, et al (1973) Moderate sodium restriction and diuretics in the treatment of hypertension. Am Heart J 85: 22PubMedCrossRefGoogle Scholar
  27. 27.
    Morgan T, Adam W, Gillies A, et al (1978) Hypertension treated by salt restriction. Lancet 1: 227PubMedCrossRefGoogle Scholar
  28. 28.
    Simpson FO (1979) Salt and hypertension: A sceptical review of the evidence. In: Proceedings of the 6th meeting of the international society of hypertension, Göteborg, Sweden Clinical Science 57: (Suppl 5 ) 4635, Medical Research Society and the Biochemical Society, LondonGoogle Scholar
  29. 29.
    Kirkendall WM, Conner WE, Abboud F, et al (1976) The effect of dietary sodium chloride on blood pressure, body fluids, electrolytes, renal function and serum lipids of normotensive man. J Lab Clin Med 87: 418Google Scholar
  30. 30.
    Mark AL, Lawton WJ, Aboud FM, et al (1975) Effects of high and low sodium intake on arterial pressure and forearm vascular resistance in borderline hypertension. Circ Res 36 (Suppl 1): 194PubMedGoogle Scholar
  31. 31.
    Kawasaki T, Delea CS, Bartter FC, et al (1978) The effect of high sodium and low sodium intakes on blood pressures and other related variables in human subjects with idiopathic hypertension. Am J Med 64: 193PubMedCrossRefGoogle Scholar
  32. 32.
    Murray RH, Luft FC, Bloch R, Weyman AE (1978) Blood pressure responses to extremes of sodium intake in normal man. Proc Soc Exp Biol Med 159: 432PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1981

Authors and Affiliations

  • George Pickering

There are no affiliations available

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