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Australian Therapeutic Trial in Mild Hypertension

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Frontiers in Hypertension Research
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Abstract

The Australian National Blood Pressure Study was a controlled therapeutic trial of antihypertensive drug treatment in 3,427 men and women aged 30–69 years. The subjects were recruited from the general population by community screening. Persons whose average diastolic blood pressure (DBP), measured twice on each of two occasions, was within the defined mild range, and who had no exclusion factors (Table 1), were eligible to enter the study. The defined mild range of hypertension was an average DBP of 95–109 mmHg with a systolic blood pressure (SBP) of less than 200 mmHg. Eligible subjects who agreed to enter the study were randomly allocated with stratification of age and sex to take either pharmacologically active tablets or matching placebo tablets.

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References

  1. Cox RD (1972) Regression models and life tables. J R Stat Soc (Series B) 34: 187–220

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  2. Hypertension Detection and Follow-up Program Cooperative Group (1979) Five-year findings of the hypertension detection and follow-up program: I. Reduction in mortality of persons with high blood pressure, including mild hypertension. JAMA 242: 2562– 2571

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© 1981 Springer-Verlag New York Inc.

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Doyle, A.E. (1981). Australian Therapeutic Trial in Mild Hypertension. In: Laragh, J.H., Bühler, F.R., Seldin, D.W. (eds) Frontiers in Hypertension Research. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5899-5_6

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  • DOI: https://doi.org/10.1007/978-1-4612-5899-5_6

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-5901-5

  • Online ISBN: 978-1-4612-5899-5

  • eBook Packages: Springer Book Archive

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