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Recent Achievements with Drosophila as an Assay System for Carcinogens

  • E. Vogel
Part of the Topics in Environmental Physiology and Medicine book series (TEPHY)

Abstract

About 1911, T.H. Morgan began genetic studies with Drosophila. Since then the work with Drosophila has been greatly extended, because this test organism combines a eukaryotic organization with a unique range of test systems. Drosophila is the only in vivo test organism which permits the simultaneous and efficient testing of the various types of genetic lesions from the molecular to the chromosome level. Stocks are available or can be constructed to test in gonadal or somatic tissues for gene mutations, deletions, and for almost all possible types of chromosome rearrangements. Special test protocols have been devised to recover aneuploidy resulting from nondisjunctional events.

Keywords

Vinyl Chloride Mutagenic Activity Pyrrolizidine Alkaloid Recent Achievement Aryl Hydrocarbon Hydroxylase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag New York Inc. 1981

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  • E. Vogel

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