Malignant Tumors

  • William P. LongmireJr.
  • Ronald K. Tompkins
Part of the Comprehensive Manuals of Surgical Specialties book series (CMSS)


Primary hepatic cancer is rare in North and South America, Europe, Russia, and Australia. In contrast, the disease has a very high incidence in Southeast Asia, China, and Africa. In some tribes among the black population south of the Sahara, cancer of the liver is the most common abdominal malignancy in males. The incidence of liver cancer among blacks in the United States is similar to that in the white population, which strongly suggests an external causative factor such as the aflatoxins B and G of the mold Aspergillus flavus, known to be a contaminant of foodstuffs in the diet of some African people with a high incidence of hepatoma. In some parts of the world the association of hepatoma with parasitic infestations, such as schistosomiasis and clonorchiasis, has been noted, but the relationship remains obscure. Cycasin from cycad nuts may produce hepatic as well as renal and other neoplasms. In a previous report, 74 of 144 patients with primary carcinoma of the liver seen at the UCLA and Wadsworth Veterans Administration Hospitals had proved cirrhosis of the liver [32]; 54 of these patients had a previous history of alcoholism and 8 had hepatitis.


Hepatic Artery Hepatic Resection Hepatic Metastasis Intrahepatic Bile Duct Primary Liver Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag New York Inc. 1981

Authors and Affiliations

  • William P. LongmireJr.
    • 1
  • Ronald K. Tompkins
    • 2
  1. 1.Department of SurgeryUCLA School of MedicineLos AngelesUSA
  2. 2.UCLA School of MedicineLos AngelesUSA

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