Abstract
Cell culture techniques provide the investigator with a means for examining the influence of the external environment of cells on intracellular metabolic processes. Since the liver plays such a critical role in the metabolism of trace elements, some years ago we initiated a project wherein the metabolism of trace elements was examined at the level of the isolated rat liver parenchymal cell. This approach has proved to be of immense importance in studies on intermediary metabolism and the mechanism of protein synthesis (1–6).
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R. F. Kleitzien, M.W. Pariza, J.E. Becker, V.R. Potter and F.R. Butcher, J. Biol. Chem., 251, 3014 (1976).
R. J. Bonney, J. E. Becker, P. R. Walker and V. R. Potter, In Vitro, 9, 399 (1974).
S. Odashima, J. M. Sturgess and A. Rothstein, Cell Tissue Res., 169, 167 (1976).
M. W. Pariza, F. R. Butcher, J. E. Becker and V. R. Potter, Proc. Natl. Acad. Sci., U. S. 74, 234 (1977).
L. J. Haars and H. C. Pitot, J. Biol. Chem., 254, 9401 (1979).
R. G. Rupp and G. M. Fuller, Biochem. Biophys. Res. Comm., 88, 327 (1979).
M. N. Berry and D. S. Friend, J. Cell Biol. 43, 506 (1969).
P. O. Seglen, Exptl. Cell Res. 82, 391 (1973).
B. A. Laishes and G. M. Williams, In Vitro, 12, 521, (1976).
G. M. Williams, E. Bermudez, R. H. San, P. J. Goldblatt, In Vitro, 14, 824 (1978).
G. Michalopoulos and H. C. Pitot, Exp. Cell Res. 94, 70 (1975).
J. A. Gurr and V. R. Potter in “Differentiation and Carcinogenesis in Liver Cell Cultures,” C. Borek and G. M. Williams, Eds., New York Acad. Sci., New York, 1980.
M. L. Failla and R. J. Cousins, Biochem. Biophys. Acta, 538, 435 (1978).
A. L. Weiner and R. J. Cousins, Biochem. Biophys. Acta, 629, 113 (1980).
M. L. Failla, R. J. Cousins and M. J. Mascenik, BioChem. Biophys. Acta, 583, 63 (1979).
M. L. Failla and R. J. Cousins, Biochem. Biophys. Acta, 543, 293 (1978).
Aronow in “Glucocorticoid Hormone Action,” J. D. Baxter and G. G. Rousseau, Eds., Springer Verlag, New York, 1979.
K. R. Etzel, S. G. Shapiro and R. J. Cousins, Biochem. Biophys. Res. Comm., 89, 1120 (1979).
S. R. Quinones, L. F. Estes and R. J. Cousins, unpublished observations.
K. R. Etzel and R. J. Cousins, Proc. Exp. Biol. Med., 167, 233 (1981).
R. J. Cousins, Nutrition Reviews, 37, 97 (1979).
A. L. Weiner and R. J. Cousins, in “Trace Elements in the Pathogenesis and Treatment of Inflammation,” K. D. Rainsford, K. Brune and M. W. Whitehouse, Eds., Birkhauser Verlag, Basel, 1981, p. 51.
A. L. Weiner and R. J. Cousins, manuscript in preparation.
E. Frieden in “Biological Roles of Copper,” Ciba Foundation 79 (new series), Excerpta Medica, 1980, p. 93.
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Cousins, R.J., Weiner, A.L. (1982). Hormonal Regulation of Copper and Zinc Metabolism in Isolated Rat Liver Parenchymal Cells. In: Sorenson, J.R.J. (eds) Inflammatory Diseases and Copper. Experimental Biology and Medicine, vol 2. Humana Press. https://doi.org/10.1007/978-1-4612-5829-2_15
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DOI: https://doi.org/10.1007/978-1-4612-5829-2_15
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