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Cell-Mediated Immunity in Autoimmune Disease

  • Chapter
Clinical Cellular Immunology

Part of the book series: Contemporary Immunology ((CONTIM))

Abstract

The history of cell-mediated immunity began before the turn of the century with the description by Koch of the delayed hypersensitivity reaction following infection by tubercle bacilli. Dienes many years later (1936) was the first to consider delayed hypersensitivity as an independent branch of the immunological response rather than a unique response to infectious microorganisms. He was successful in producing delayed hypersensitivity by injecting nonliving protein antigens into tuberculous foci.

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Burek, C.L., Rose, N.R., Lillehoj, H.S. (1982). Cell-Mediated Immunity in Autoimmune Disease. In: Luderer, A.A., Weetall, H.H. (eds) Clinical Cellular Immunology. Contemporary Immunology. Humana Press. https://doi.org/10.1007/978-1-4612-5802-5_6

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