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The T Cell Antigen Receptor

Structural and Functional Considerations
  • Albert A. Luderer
  • Michael A. Harvey
Part of the Contemporary Immunology book series (CONTIM)

Abstract

Initiation of the immune response following antigenic challenge begins with the specific interaction of epitopes on the antigen- and plasma membrane-associated receptors found on the cell surface of lymphocytes. Certainly the interaction of antigen with both regulatory and effector thymus-derived lymphocytes (T cells) is a critical event in this process. According to clonal selection theories (Burnett, 1969), antigen initially interacts with a relatively small number of T cells that exhibit antigen receptors of the appropriate specificity.

Keywords

Cell Receptor Radioreceptor Assay Cell Antigen Receptor Clonal Selection Theory Cell Receptor Repertoire 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© The Humana Press Inc. 1982

Authors and Affiliations

  • Albert A. Luderer
    • 1
  • Michael A. Harvey
    • 1
  1. 1.Biosciences Research Department, Research and Development DivisionCorning Glass WorksCorningUSA

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