Development of Cholinergic and Amino Acid Neurotransmitter Systems in the Chick Retina

  • Robert Baughman
Conference paper
Part of the Cell and Developmental Biology of the Eye book series (EYE)


The presence of a cholinergic system in many vertebrate retinas is well established from biochemical and physiological experiments (Lindeman, 1947; Hebb, 1957; Graham, 1974; Ross and McDougal, 1976; Masland and Ames, 1976; Baughman and Bader, 1977). The first cellular localization of this system was achieved by the use of an autoradiographic technique with chick retina (Baughman and Bader, 1977). A similar technique was applied with similar results in the rabbit retina (Masland and Mills, 1979).


Cholinergic System Choline Acetyltransferase Vertebrate Retina Rabbit Retina Chick Retina 
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  1. Bader, C.R., R.W. Baughman and J.L. Moore. 1978. Different time course development for high-affinity choline uptake and choline acetyltransferase in the chick retina. Proc. Natl. Acad. Sci. USA 75: 2525–2529.PubMedCrossRefGoogle Scholar
  2. Baughman, R.W. and C.R. Bader. 1977. Biochemical characterization and cellular localization of the cholinergic system in the chicken retina. Brain Research 138; 469–485.PubMedCrossRefGoogle Scholar
  3. Baughman, R.W. and C.D. Gilbert. 1981. Aspartate and glutamate as possible neurotransmitters in the visual cortex. J. Neurosci. 1: 427–439.PubMedGoogle Scholar
  4. Fisher, D.E., J.F. Amend and D.H. Strumeyer. 1977. Anserine and carnosine in chicks (Gallus gallus) rat pups (Rattus rattus) and ducklings (Anas platyrhynchos): comparative ontogenetic observations. Comp. Biochem. Physiol. 56B: 367–370.Google Scholar
  5. Graham, L.T. 1974. Comparative aspects of neurotransmitters in the retina. In“The Eye”, (H. Davson and L.T. Graham, Eds.), Vol. 6, Academic Press, New York, pp. 283–342.Google Scholar
  6. Hebb, C. 1957. Biochemical evidence for the neural function of acetylcholine. Physiol. Rev. 37: 169–220.Google Scholar
  7. Lindeman, V.F. 1947. The cholinesterse and acetylcholine content of the chick retina, with special reference to functional activity as indicated by the pupillary constrictor reflex. Amer. J. Physiol. 148: 40–44.PubMedGoogle Scholar
  8. Masland, R.H. and A. Ames III. 1976. Responses to acetylcholine of ganglion cells in an isolated mammalian retina. J.. Neurophysiol. 39: 1220–1235.PubMedGoogle Scholar
  9. Masland, R.H. and J.W. Mills. 1979. Autoradiographic identification of acetylcholine in the rabbit retina. J. Cell Biol. 83: 159–178.PubMedCrossRefGoogle Scholar
  10. Pasantes-Morales, H., J. Klethi, M. Ledig and P. Mandel. 1973. Influence of light and dark on the free amino acid pattern of the developing chick retina. Brain Research 57: 59–65.PubMedCrossRefGoogle Scholar
  11. Ross, C.D. and D.B. McDougal. 1976. The distribution of choline acetyltransferase in vetebrate retina. J. Neurochem. 26: 521–526.PubMedCrossRefGoogle Scholar

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© Springer-Verlag New York Inc. 1982

Authors and Affiliations

  • Robert Baughman

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